Nuclease activity of tal effector and foki fusion protein
作者： Sheng Huang , Bing Yang , Ting Li
DOI:
关键词:
摘要: The present invention provides compositions and methods for targeted cleavage of cellular chromatin in a region interest and/or homologous recombination at predetermined site cells. Compositions include fusion polypeptides comprising TAL effector binding domain domain. can be from any endonuclease. In certain embodiments, the endonuclease is Type IIS restriction further Fokl.
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