Targeted Sequencing of Cancer-Related Genes in Colorectal Cancer Using Next-Generation Sequencing

Matthew Meyerson, Stacey Gabriel, Gad Getz, Advances in understanding cancer genomes through second-generation sequencing Nature Reviews Genetics. ,vol. 11, pp. 685- 696 ,(2010) , 10.1038/NRG2841

Prateek Kumar, Steven Henikoff, Pauline C Ng, Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm. Nature Protocols. ,vol. 4, pp. 1073- 1081 ,(2009) , 10.1038/NPROT.2009.86

J. C. Lin, J. Cummins, S. Boca, L. D. Wood, D. W. Parsons, S. Jones, T. Sjoblom, B.-H. Park, R. Parsons, J. Willis, D. Dawson, J. K. V. Willson, T. Nikolskaya, Y. Nikolsky, L. Kopelovich, N. Papadopoulos, L. A. Pennacchio, T.-L. Wang, S. D. Markowitz, G. Parmigiani, K. W. Kinzler, B. Vogelstein, V. E. Velculescu, R. J. Leary, Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers Proceedings of the National Academy of Sciences of the United States of America. ,vol. 105, pp. 16224- 16229 ,(2008) , 10.1073/PNAS.0808041105

L. D. Wood, D. W. Parsons, S. Jones, J. Lin, T. Sjoblom, R. J. Leary, D. Shen, S. M. Boca, T. Barber, J. Ptak, N. Silliman, S. Szabo, Z. Dezso, V. Ustyanksky, T. Nikolskaya, Y. Nikolsky, R. Karchin, P. A. Wilson, J. S. Kaminker, Z. Zhang, R. Croshaw, J. Willis, D. Dawson, M. Shipitsin, J. K. V. Willson, S. Sukumar, K. Polyak, B. H. Park, C. L. Pethiyagoda, P. V. K. Pant, D. G. Ballinger, A. B. Sparks, J. Hartigan, D. R. Smith, E. Suh, N. Papadopoulos, P. Buckhaults, S. D. Markowitz, G. Parmigiani, K. W. Kinzler, V. E. Velculescu, B. Vogelstein, Genomic landscapes of human breast and colorectal cancers Science. ,vol. 318, pp. 1108- 1113 ,(2008) , 10.1126/SCIENCE.1145720

Adam J Bass, Michael S Lawrence, Lear E Brace, Alex H Ramos, Yotam Drier, Kristian Cibulskis, Carrie Sougnez, Douglas Voet, Gordon Saksena, Andrey Sivachenko, Rui Jing, Melissa Parkin, Trevor Pugh, Roel G Verhaak, Nicolas Stransky, Adam T Boutin, Jordi Barretina, David B Solit, Evi Vakiani, Wenlin Shao, Yuji Mishina, Markus Warmuth, Jose Jimenez, Derek Y Chiang, Sabina Signoretti, William G Kaelin, Nicole Spardy, William C Hahn, Yujin Hoshida, Shuji Ogino, Ronald A DePinho, Lynda Chin, Levi A Garraway, Charles S Fuchs, Jose Baselga, Josep Tabernero, Stacey Gabriel, Eric S Lander, Gad Getz, Matthew Meyerson, None, Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A - TCF7L2 fusion Nature Genetics. ,vol. 43, pp. 964- 968 ,(2011) , 10.1038/NG.936

Jung Ho Kim, So Hyun Shin, Hyeong Ju Kwon, Nam Yun Cho, Gyeong Hoon Kang, Prognostic implications of CpG island hypermethylator phenotype in colorectal cancers Virchows Archiv. ,vol. 455, pp. 485- 494 ,(2009) , 10.1007/S00428-009-0857-0

C. Richard Boland, Ajay Goel, Microsatellite Instability in Colorectal Cancer Gastroenterology. ,vol. 138, pp. 2073- 2087 ,(2010) , 10.1053/J.GASTRO.2009.12.064

Sanford D. Markowitz, Monica M. Bertagnolli, Molecular Basis of Colorectal Cancer The New England Journal of Medicine. ,vol. 361, pp. 2449- 2460 ,(2009) , 10.1056/NEJMRA0804588

T. D. Wu, S. Nacu, Fast and SNP-tolerant detection of complex variants and splicing in short reads Bioinformatics. ,vol. 26, pp. 873- 881 ,(2010) , 10.1093/BIOINFORMATICS/BTQ057

Yung-Jue Bang, Eric Van Cutsem, Andrea Feyereislova, Hyun C Chung, Lin Shen, Akira Sawaki, Florian Lordick, Atsushi Ohtsu, Yasushi Omuro, Taroh Satoh, Giuseppe Aprile, Evgeny Kulikov, Julie Hill, Michaela Lehle, Josef Rüschoff, Yoon-Koo Kang, None, Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial The Lancet. ,vol. 376, pp. 687- 697 ,(2010) , 10.1016/S0140-6736(10)61121-X