Heterogeneity of Genetic Changes Associated with Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancer

作者: Soyeon Kim , Tae Min Kim , Dong-Wan Kim , Heounjeong Go , Bhumsuk Keam

DOI: 10.1097/JTO.0B013E318283DCC0

关键词:

摘要: … Anaplastic lymphoma kinase (ALK)-rearranged non–small-cell lung cancer (NSCLC) is markedly sensitive to the ALK inhibitor crizotinib. However, acquired resistance to crizotinib is …

参考文章(20)
Daisy Wing-Sze Wong, Elaine Lai-Han Leung, Sunny Kit-Man Wong, Vicky Pui-Chi Tin, Alan Dart-Loon Sihoe, Lik-Cheung Cheng, Joseph Siu-Kie Au, Lap-Ping Chung, Maria Pik Wong, A novel KIF5B-ALK variant in nonsmall cell lung cancer. Cancer. ,vol. 117, pp. 2709- 2718 ,(2011) , 10.1002/CNCR.25843
Sen Zhang, Frank Wang, Jeffrey Keats, Xiaotian Zhu, Yaoyu Ning, Scott D. Wardwell, Lauren Moran, Qurish K. Mohemmad, Rana Anjum, Yihan Wang, Narayana I. Narasimhan, David Dalgarno, William C. Shakespeare, Juan J. Miret, Tim Clackson, Victor M. Rivera, Crizotinib-resistant mutants of EML4-ALK identified through an accelerated mutagenesis screen. Chemical Biology & Drug Design. ,vol. 78, pp. 999- 1005 ,(2011) , 10.1111/J.1747-0285.2011.01239.X
June Koo Lee, Heae Surng Park, Dong‐Wan Kim, Kimary Kulig, Tae Min Kim, Se‐Hoon Lee, Yoon‐Kyung Jeon, Doo Hyun Chung, Dae Seog Heo, Woo‐Ho Kim, Yung‐Jue Bang, None, Comparative analyses of overall survival in patients with anaplastic lymphoma kinase‐positive and matched wild‐type advanced nonsmall cell lung cancer Cancer. ,vol. 118, pp. 3579- 3586 ,(2012) , 10.1002/CNCR.26668
Young Lim Choi, Manabu Soda, Yoshihiro Yamashita, Toshihide Ueno, Junpei Takashima, Takahiro Nakajima, Yasushi Yatabe, Kengo Takeuchi, Toru Hamada, Hidenori Haruta, Yuichi Ishikawa, Hideki Kimura, Tetsuya Mitsudomi, Yoshiro Tanio, Hiroyuki Mano, EML4-ALK Mutations in Lung Cancer That Confer Resistance to ALK Inhibitors The New England Journal of Medicine. ,vol. 363, pp. 1734- 1739 ,(2010) , 10.1056/NEJMOA1007478
Susumu Kobayashi, Titus J. Boggon, Tajhal Dayaram, Pasi A. Jänne, Olivier Kocher, Matthew Meyerson, Bruce E. Johnson, Michael J. Eck, Daniel G. Tenen, Balázs Halmos, EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib The New England Journal of Medicine. ,vol. 352, pp. 786- 792 ,(2005) , 10.1056/NEJMOA044238
D. Ross Camidge, Robert C. Doebele, Treating ALK-positive lung cancer—early successes and future challenges Nature Reviews Clinical Oncology. ,vol. 9, pp. 268- 277 ,(2012) , 10.1038/NRCLINONC.2012.43
Manabu Soda, Young Lim Choi, Munehiro Enomoto, Shuji Takada, Yoshihiro Yamashita, Shunpei Ishikawa, Shin-ichiro Fujiwara, Hideki Watanabe, Kentaro Kurashina, Hisashi Hatanaka, Masashi Bando, Shoji Ohno, Yuichi Ishikawa, Hiroyuki Aburatani, Toshiro Niki, Yasunori Sohara, Yukihiko Sugiyama, Hiroyuki Mano, None, Identification of the transforming EML4–ALK fusion gene in non-small-cell lung cancer Nature. ,vol. 448, pp. 561- 566 ,(2007) , 10.1038/NATURE05945
Robert C. Doebele, Amanda B. Pilling, Dara L. Aisner, Tatiana G. Kutateladze, Anh T. Le, Andrew J. Weickhardt, Kimi L. Kondo, Derek J. Linderman, Lynn E. Heasley, Wilbur A. Franklin, Marileila Varella-Garcia, D. Ross Camidge, Mechanisms of Resistance to Crizotinib in Patients with ALK Gene Rearranged Non-Small Cell Lung Cancer Clinical Cancer Research. ,vol. 18, pp. 1472- 1482 ,(2012) , 10.1158/1078-0432.CCR-11-2906
Leora Horn, William Pao, EML4-ALK: honing in on a new target in non-small-cell lung cancer. Journal of Clinical Oncology. ,vol. 27, pp. 4232- 4235 ,(2009) , 10.1200/JCO.2009.23.6661
Eunice L. Kwak, Yung-Jue Bang, D. Ross Camidge, Alice T. Shaw, Benjamin Solomon, Robert G. Maki, Sai-Hong I. Ou, Bruce J. Dezube, Pasi A. Jänne, Daniel B. Costa, Marileila Varella-Garcia, Woo-Ho Kim, Thomas J. Lynch, Panos Fidias, Hannah Stubbs, Jeffrey A. Engelman, Lecia V. Sequist, WeiWei Tan, Leena Gandhi, Mari Mino-Kenudson, Greg C. Wei, S. Martin Shreeve, Mark J. Ratain, Jeffrey Settleman, James G. Christensen, Daniel A. Haber, Keith Wilner, Ravi Salgia, Geoffrey I. Shapiro, Jeffrey W. Clark, A. John Iafrate, Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer The New England Journal of Medicine. ,vol. 363, pp. 1693- 1703 ,(2010) , 10.1056/NEJMOA1006448