Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas

作者: K. Fransen

DOI: 10.1093/CARCIN/BGH049

关键词:

摘要: … MAPKKK BRAF gene were found in colorectal cancer cell … normal genomic DNA were amplified in 20 µl PCR reactions as … primers were used for amplification of the ARAF , BRAF , RAF-…

参考文章(28)
Annie M. Young, D.J. Kerr, F.D. Richard Hobbs, ABC of colorectal cancer : BMJ Books. ,(2011)
Allan Sirsjö, Peter Söderkvist, Anders Hugander, Jan Dimberg, Enhanced expression of cyclooxygenase-2 and nuclear beta-catenin are related to mutations in the APC gene in human colorectal cancer. Anticancer Research. ,vol. 21, pp. 911- 915 ,(2001)
Marcia S Brose, Patricia Volpe, Michael Feldman, Madhu Kumar, Irum Rishi, Renee Gerrero, Eugene Einhorn, Meenhard Herlyn, John Minna, Andrew Nicholson, Jack A Roth, Steven M Albelda, Helen Davies, Charles Cox, Graham Brignell, Philip Stephens, P Andrew Futreal, Richard Wooster, Michael R Stratton, Barbara L Weber, None, BRAF and RAS mutations in human lung cancer and melanoma Cancer Research. ,vol. 62, pp. 6997- 7000 ,(2002)
J. R. Jass, K. G. Biden, M. C. Cummings, L. A. Simms, M. Walsh, E. Schoch, S. J. Meltzer, C. Wright, J. Searle, J. Young, B. A. Leggett, Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways. Journal of Clinical Pathology. ,vol. 52, pp. 455- 460 ,(1999) , 10.1136/JCP.52.6.455
Carole Peyssonnaux, Alain Eychène, The Raf/MEK/ERK pathway: new concepts of activation Biology of the Cell. ,vol. 93, pp. 53- 62 ,(2001) , 10.1016/S0248-4900(01)01125-X
Harith Rajagopalan, Alberto Bardelli, Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein, Victor E. Velculescu, Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status. Nature. ,vol. 418, pp. 934- 934 ,(2002) , 10.1038/418934A
Anna Österström, Jan Dimberg, Karin Fransén, Peter Söderkvist, Expression of cytosolic and group X secretory phospholipase A2 genes in human colorectal adenocarcinomas Cancer Letters. ,vol. 182, pp. 175- 182 ,(2002) , 10.1016/S0304-3835(02)00081-2
Eric R. Fearon, Bert Vogelstein, A genetic model for colorectal tumorigenesis Cell. ,vol. 61, pp. 759- 767 ,(1990) , 10.1016/0092-8674(90)90186-I
G. Smith, F. A. Carey, J. Beattie, M. J. V. Wilkie, T. J. Lightfoot, J. Coxhead, R. C. Garner, R. J. C. Steele, C. R. Wolf, Mutations in APC, Kirsten-ras, and p53—alternative genetic pathways to colorectal cancer Proceedings of the National Academy of Sciences of the United States of America. ,vol. 99, pp. 9433- 9438 ,(2002) , 10.1073/PNAS.122612899
Carsten Hagemann, Ulf R. Rapp, Isotype-specific functions of Raf kinases. Experimental Cell Research. ,vol. 253, pp. 34- 46 ,(1999) , 10.1006/EXCR.1999.4689