Effect of temozolomide treatment on the adenine nucleotide hydrolysis in blood serum of rats with implanted gliomas

摘要: Correspondence Fernanda B Morrone Faculdade de Farmacia Pontificia Universidade Catolica do RS Av. Ipiranga, 6681 P. 12 Bl. C Sala 148 90619900 Porto Alegre,Brasil Phone: +55 51 33203512 E-mail: fbmorrone@gmail.com ATP and other nucleotides nucleosides are very important signaling molecules under physiological pathological conditions in the central nervous system. The events induced by extracellular adenine controlled action of ectonucleotidases, which hydrolyze into adenosine space. Our group has shown involvement purinergic system glioma proliferation different cell types. Low concentrations Introduction