Assessment of EGFR Mutation Status in Lung Adenocarcinoma by Immunohistochemistry Using Antibodies Specific to the Two Major Forms of Mutant EGFR

作者: Marie Brevet , Maria Arcila , Marc Ladanyi

DOI: 10.2353/JMOLDX.2010.090140

关键词:

摘要: … on EGFR TKIs than with conventional cytotoxic chemotherapy. EGFR-mutant lung adenocarcinomas also form a distinct clinically favorable biological subset, regardless of EGFR TKI …

参考文章(16)
Allan R. Li, Dhananjay Chitale, Gregory J. Riely, William Pao, Vincent A. Miller, Maureen F. Zakowski, Valerie Rusch, Mark G. Kris, Marc Ladanyi, EGFR Mutations in Lung Adenocarcinomas: Clinical Testing Experience and Relationship to EGFR Gene Copy Number and Immunohistochemical Expression The Journal of Molecular Diagnostics. ,vol. 10, pp. 242- 248 ,(2008) , 10.2353/JMOLDX.2008.070178
Valerie W. Rusch, Mark G. Kris, Marc Ladanyi, Michelle S. Ginsberg, Vincent A. Miller, William Pao, Robert Heelan, Maureen F. Zakowski, Sanaa Hussain, Morphologic features of adenocarcinoma of the lung predictive of response to the epidermal growth factor receptor kinase inhibitors erlotinib and gefitinib. Archives of Pathology & Laboratory Medicine. ,vol. 133, pp. 470- 477 ,(2009) , 10.1043/1543-2165-133.3.470
Sreenath V. Sharma, Daphne W. Bell, Jeffrey Settleman, Daniel A. Haber, Epidermal growth factor receptor mutations in lung cancer Nature Reviews Cancer. ,vol. 7, pp. 169- 181 ,(2007) , 10.1038/NRC2088
William Pao, Marc Ladanyi, Epidermal growth factor receptor mutation testing in lung cancer: searching for the ideal method. Clinical Cancer Research. ,vol. 13, pp. 4954- 4955 ,(2007) , 10.1158/1078-0432.CCR-07-1387
Qiulu Pan, William Pao, Marc Ladanyi, Rapid Polymerase Chain Reaction-Based Detection of Epidermal Growth Factor Receptor Gene Mutations in Lung Adenocarcinomas The Journal of Molecular Diagnostics. ,vol. 7, pp. 396- 403 ,(2005) , 10.1016/S1525-1578(10)60569-7
Jenifer L. Marks, Stephen Broderick, Qin Zhou, Dhananjay Chitale, Allan R. Li, Maureen F. Zakowski, Mark G. Kris, Valerie W. Rusch, Christopher G. Azzoli, Venkatraman E. Seshan, Marc Ladanyi, William Pao, Prognostic and Therapeutic Implications of EGFR and KRAS Mutations in Resected Lung Adenocarcinoma Journal of Thoracic Oncology. ,vol. 3, pp. 111- 116 ,(2008) , 10.1097/JTO.0B013E318160C607
Marc Ladanyi, William Pao, Lung adenocarcinoma: guiding EGFR-targeted therapy and beyond. Modern Pathology. ,vol. 21, ,(2008) , 10.1038/MODPATHOL.3801018
Hidefumi Sasaki, Katsuhiko Endo, Haruhiro Yukiue, Yoshihiro Kobayashi, Motoki Yano, Yoshitaka Fujii, Mutation of epidermal growth factor receptor gene in adenosquamous carcinoma of the lung. Lung Cancer. ,vol. 55, pp. 129- 130 ,(2007) , 10.1016/J.LUNGCAN.2006.09.003
Shin Myung Kang, Hyun Ju Kang, Ju Hye Shin, Hoguen Kim, Dong Hwan Shin, Se Kyu Kim, Joo-Hang Kim, Kyung Young Chung, Sung Kyu Kim, Joon Chang, Identical epidermal growth factor receptor mutations in adenocarcinomatous and squamous cell carcinomatous components of adenosquamous carcinoma of the lung Cancer. ,vol. 109, pp. 581- 587 ,(2007) , 10.1002/CNCR.22413
Yuji Sakuma, Shoichi Matsukuma, Mitsuyo Yoshihara, Yoshiyasu Nakamura, Kazumasa Noda, Haruhiko Nakayama, Yoichi Kameda, Eiju Tsuchiya, Yohei Miyagi, Distinctive evaluation of nonmucinous and mucinous subtypes of bronchioloalveolar carcinomas in EGFR and K-ras gene-mutation analyses for Japanese lung adenocarcinomas: confirmation of the correlations with histologic subtypes and gene mutations. American Journal of Clinical Pathology. ,vol. 128, pp. 100- 108 ,(2007) , 10.1309/WVXFGAFLAUX48DU6