Studies on the neurotrophic factor Manf and the pleiotropic factor Lin-28 during Drosophila development
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摘要: REVIEW OF THE LITERATURE 1 DROSOPHILA AS A MODEL SYSTEM NEUROBIOLOGY: STUDY NERVOUS NEUROTROPHIC FACTORS IN VERTEBRATES AND THEIR CLASSIFICATION 2 INVERTEBRATES 7 Drosophila Neurotrophins (DNTs) MANF (DmMANF) 8 Glia 9 Microglia –The macrophages of the vertebrate nervous system IMMUNITY 10 Cellular immune response 11 Humoral 12 Immunity in brain 14 AUTOPHAGY OOGENESIS 15 LIN-28 LET-7 16 AIMS 19 MATERIALS METHODS 20 TABLE 1. 2. FLY STRAINS 21 3. ANTIBODIES 23 RESULTS DISCUSSION 24 DMMANF EXPRESSION ADULT CNS (III-IV) DmMANF expression adult non-neuronal tissues (III) vivo functional studies with focus to dopaminergic (IV)..... 25 overexpression does not affect (IV) is required a cell autonomous fashion for survival and differentiation main types 26
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