Differential gene expression changes in children with severe dengue virus infections.

作者: Martijn D. de Kruif , Tatty E. Setiati , Albertus T. A. Mairuhu , Penelopie Koraka , Hella A. Aberson

DOI: 10.1371/JOURNAL.PNTD.0000215

关键词:

摘要: Background The host response to dengue virus infection is characterized by the production of numerous cytokines, but overall picture appears be complex. It has been suggested that a balance may involved between protective and pathologic immune responses. This study aimed define differential responses in association with clinical outcomes gene expression profiling selected panel inflammatory genes whole blood samples from children severe infections.

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