PREVENTION OF SPINAL OSTEOPOROSIS IN OOPHORECTOMISED WOMEN

摘要: 100 women who had taken part in a prospective controlled trial of oestrogen therapy for prevention post-oophorectomy bone loss were reviewed after median follow-up period nine years. A significant reduction height occurred among the placebo-treated group, but not group treated with mestranol (mean 23 x 3 micrograms/day). The higher spine score, lower central vertebral height, and larger wedge-angle than group. Within each none these spinal morphometric changes correlated mineral content metacarpal or radial bones as measured by photon absorptiometry X-ray densitometry, although both peripheral measurements showed highly differences between groups. Oestrogen treatment, therefore, prevents against central, well peripheral, loss, reduces incidence compression.