作者: George A. Poultsides , Elliot L. Servais , Leonard B. Saltz , Sujata Patil , Nancy E. Kemeny
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摘要: Purpose The purpose of this study was to describe the frequency interventions necessary palliate intact primary tumor in patients who present with synchronous, stage IV colorectal cancer (CRC) and receive up-front modern combination chemotherapy without prophylactic surgery. Patients Methods By using a prospective institutional database, we identified 233 consecutive from 2000 through 2006 synchronous metastatic CRC an unresected received oxaliplatin- or irinotecan-based, triple-drug (infusional fluorouracil, leucovorin, oxaliplatin; bolus irinotecan; irinotecan) bevacizumab as their initial treatment. incidence subsequent use surgery, radiotherapy, and/or endoluminal stenting manage complications recorded. Results Of patients, 217 (93%) never required surgical palliation tumor. Sixteen (7%) requir...