[20] Computational Analyses Aiding Identification and Characterization of Proteins, Genes, and Operons

摘要: Publisher Summary This chapter discusses the utility of computer techniques, approached from rationale molecular biologists, for correction sequencing and assignment errors gleaning maximal information DNA sequence data. Computer-aided approaches facilitate proper identification characterization operon, gene, protein structures. The use these is exemplified in chapter, drawing on a large body representative published data concerned primarily with operons, including genes encoding proteins phosphoenolpyruvate:sugar phosphotransferase system (PTS) other transport systems. human element implies that genome sequences will be riddled errors, can recognized when appropriate tools are applied. brain lacks many capacities computer. Although an indispensible helpmate searching comparing sequences, biochemists biologists must guard against blind acceptance any sophisticated algorithmic output.