Reactive oxygen species in the progression of CCl4-induced liver injury.
作者： I. G. Sipes , A. E. El Sisi , W. W. Sim , S. A. Mobley , D. L. Earnest
DOI: 10.1007/978-1-4684-5877-0_65
关键词:
摘要: Pretreatment of rats with large doses vitamin A (retinol) dramatically increased the hepatotoxicity carbon tetrachloride (CCl4). Experiments were performed to elucidate mechanism this potentiation. Hypervitaminosis was produced by oral administration retinol, 250,000 IU/kg for seven days. CCl4 then administered at a dose 0.15 ml/kg, ip.
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