Asthma and current intestinal parasite infection: systematic review and meta-analysis.
作者： Jo Leonardi-Bee , David Pritchard , John Britton ,
DOI: 10.1164/RCCM.200603-331OC
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摘要: Rationale: Epidemiologic studies suggest that intestinal parasite infections may protect against asthma.Objectives: A systematic review and meta-analysis of epidemiologic to determine whether total or species-specific current infection is associated with a reduced risk asthma wheeze.Methods: We searched MEDLINE, EMBASE, CINAHL (up January 2006); reviews; reference lists from publications, no language restrictions. included reported wheeze as an outcome measure ascertained by fecal examination. estimated pooled odds ratios (OR) 95% confidence intervals (CI) using data extracted published papers, where available, original provided authors, random effect models.Measurements Main Results: Thirty-three met the inclusion criteria. Infection any was small, nonsignificant increase in (OR, 1.24; CI, 0.98–1.57; 29 studies). In species-specif...
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