The yes-related cellular gene lyn encodes a possible tyrosine kinase similar to p56lck.
作者： Y Yamanashi , S Fukushige , K Semba , J Sukegawa , N Miyajima
DOI: 10.1128/MCB.7.1.237
关键词:
摘要: With v-yes DNA as the probe, a human cDNA library made from placental RNA was screened under relaxed conditions, and clones derived novel genetic locus, termed lyn, were obtained. Nucleotide sequencing revealed that lyn could encode tyrosine kinase very similar to mouse T-lymphocyte-specific p56lck protein well gene products of v-fgr v-src. Northern hybridization analysis 3.2-kilobase mRNA expressed in variety tissues fetus. The pattern expression different those related genes, such yes syn. Hybridization sorted chromosomes showed is located on chromosome 8 q13-qter.
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