Clinical Implications of Circulating Angiogenic Factors in Cancer Patients
作者： Ronnie Tung-Ping Poon , Sheung-Tat Fan , John Wong
DOI: 10.1200/JCO.2001.19.4.1207
关键词:
摘要: PURPOSE: Angiogenesis, a process fundamental to tumor growth, is regulated by angiogenic factors. This article reviews prognostic and other clinical implications of circulating factors in cancer patients. METHODS: A MEDLINE search literature was performed using the names various as key words. Studies pertaining patients were reviewed. Pertinent regarding expression common their relevance human cancers also examined. RESULTS: substantial number studies have demonstrated strong association between elevated vascular endothelial growth factor (VEGF) advanced disease or poor prognosis cancers. supports pivotal role VEGF regulating angiogenesis. More recently, there mounting evidence that level with different types may be predictive status progn...
hku.hk
sci-hub.se 参考文章(190)
Alvaro Aguayo, Elihu Estey, Hagop Kantarjian, Taghi Mansouri, Cristi Gidel, Michael Keating, Francis Giles, Zeev Estrov, Bart Barlogie, Maher Albitar, Cellular vascular endothelial growth factor is a predictor of outcome in patients with acute myeloid leukemia. Blood. ,vol. 94, pp. 3717- 3721 ,(1999) , 10.1182/BLOOD.V94.11.3717
Sun Hc, Qin Lx, Zhou J, Tang Zy, Li Xm, Serum vascular endothelial growth factor is a predictor of invasion and metastasis in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research. ,vol. 18, pp. 511- 517 ,(1999)
G Sliutz, C Kainz, A Obermair, C Dadak, C Tempfer, Serum evaluation of basic FGF in breast cancer patients. Anticancer Research. ,vol. 15, pp. 2675- 2677 ,(1995)
G Brunner, H Nguyen, J Gabrilove, DB Rifkin, EL Wilson, Basic fibroblast growth factor expression in human bone marrow and peripheral blood cells. Blood. ,vol. 81, pp. 631- 638 ,(1993) , 10.1182/BLOOD.V81.3.631.631
Julie M. Cherrington, Laurie M. Strawn, Laura K. Shawver, New paradigms for the treatment of cancer: The role of anti-angiogenesis agents Advances in Cancer Research. ,vol. 79, pp. 1- 38 ,(2000) , 10.1016/S0065-230X(00)79001-4
Liisa Pertovaara, Arja Kaipainen, Tuija Mustonen, Arto Orpana, Napoleone Ferrara, Olli Saksela, Kari Alitalo, None, Vascular endothelial growth factor is induced in response to transforming growth factor-beta in fibroblastic and epithelial cells. Journal of Biological Chemistry. ,vol. 269, pp. 6271- 6274 ,(1994) , 10.1016/S0021-9258(17)37365-9
K. Miyazono, T. Okabe, A. Urabe, F. Takaku, C.H. Heldin, Purification and properties of an endothelial cell growth factor from human platelets. Journal of Biological Chemistry. ,vol. 262, pp. 4098- 4103 ,(1987) , 10.1016/S0021-9258(18)61316-X
Christopher Corless, Kathy Niknejad, Shay Soker, Michael Klagsbrun, Michael R. Freeman, Michael L. Gagnon, Francis X. Schneck, George E. Peoples, Peripheral Blood T Lymphocytes and Lymphocytes Infiltrating Human Cancers Express Vascular Endothelial Growth Factor: A Potential Role for T Cells in Angiogenesis Cancer Research. ,vol. 55, pp. 4140- 4145 ,(1995)
Teresa Padró, Sandra Ruiz, Ralf Bieker, Horst Bürger, Martin Steins, Joachim Kienast, Thomas Büchner, Wolfgang E. Berdel, Rolf M. Mesters, Increased angiogenesis in the bone marrow of patients with acute myeloid leukemia. Blood. ,vol. 95, pp. 2637- 2644 ,(2000) , 10.1182/BLOOD.V95.8.2637
M M Davies, S K Jonas, S Kaur, T G Allen-Mersh, Plasma vascular endothelial but not fibroblast growth factor levels correlate with colorectal liver metastasis vascularity and volume British Journal of Cancer. ,vol. 82, pp. 1004- 1008 ,(2000) , 10.1054/BJOC.1999.1033