Enhancement of the dissolution rates of poorly water-soluble drugs by water-soluble gelatin.

摘要: The dissolution behavior of several acidic and basic drugs from kneaded mixtures with water-soluble gelatin have been studied in comparison that the drug alone. results revealed a significant increase rate mixtures. showed little interaction any solution or solid state. Interestingly, contact angle mixture was remarkably decreased compared powder found to be almost same as powder. Thus, enhanced caused by explained improvement wettability water.