Cytogenetic studies in twenty human brain tumors: Association of no. 22 chromosome abnormalities with tumors of the brain

摘要: Abstract The chromosomes were analyzed in cells from twenty cases of primary brain tumors cultured for short periods. There nine with chromosome abnormalities; eight these showed an abnormality involving a No. 22 chromosome. Three each pituitary adenoma and craniopharyngioma no abnormalities. In five the seven meningioma studied, hypodiploid clones caused by loss 1 to 4 observed. Detailed analysis missing chromosomes, revealed chromosome, aberration specific meningioma. Two astrocytomas case oligoden-droblastoma also abnormal possible significance association abnormalities is discussed light findings, obtained to-date, field tumor cytogenetics.