Changes in plasma somatomedin-C in response to ingestion of diets with variable protein and energy content

摘要: We have attempted to determine the relative importance of dietary intake protein and energy in restoring plasma immunoreactive somatomedin-C (Sm-C) concentrations after fasting. Ten healthy human volunteers were fasted for 5 days, then divided into two refeeding groups. One group (variable energy) was refed 1.0 g protein/kg ideal body weight, 9-day sequences, 11, 18 25 kcal energy/kg. The other protein) given 35 energy/kg, 0.2, 0.4, protein/kg. When subjects variable diets there no significant increase Sm-C at 11 kcal/kg (0.47 +/- 0.13 0.45 0.12 U/ml), suggesting that is a threshold requirement below which optimal not sufficient raise Sm-C. kcal/kg, it became apparent more added diet, greater absolute concentration attained (0.66 U/ml on 0.97 kcal/kg). correlated with nitrogen balance (r = 0.58) during good indicator acute directional change balance. However, reliable repletion, since rose almost control levels diet while remained slightly negative.(ABSTRACT TRUNCATED AT 250 WORDS)