The effect of physical activity on dose-relationship between serum 25-hydroxyvitamin D and cardiovascular health events in older adults.
作者： Yi Su , Jason Leung , Jenny Lee , Kin-fai Ho , Timothy Kwok
DOI: 10.1016/J.NUMECD.2019.12.006
关键词:
摘要: Abstract Background and aims Reverse J- or U-shaped associations between serum 25-hydroxyvitamin D (25[OH]D) concentrations cardiovascular outcomes have been reported, which need clarifications in older adults. Physical activity, correlating with both 25[OH]D concentration health, may an effect on the dose-relationships. Methods Results At baseline, 2790 participants aged 65 years over, free of vitamin supplementation use, had assays for health related characteristics measurements, were followed up events death by to 7 15 years, respectively. The dose–response mortality risk examined using Cox regression models. After adjusting physical activity other covariates, was non-linearly associated (U-shaped, P = 0.009). According Institute Medicine categories, HR(95% CI) separately deficient ( Conclusion Both lower higher Chinese community-dwelling attenuate inadequacy, but its role individuals remains unclear.
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