Clinical application of targeted next generation sequencing for colorectal cancers

作者: Quitterie Fontanges , Ricardo De Mendonca , Isabelle Salmon , Marie Le Mercier , Nicky D’Haene

DOI: 10.3390/IJMS17122117

关键词:

摘要: Promising targeted therapy and personalized medicine are making molecular profiling of tumours a priority. For colorectal cancer (CRC) patients, international guidelines made RAS (KRAS NRAS) status prerequisite for the use anti-epidermal growth factor receptor agents (anti-EGFR). Daily, new data emerge on theranostic prognostic role biomarkers, which is strong incentive validated, sensitive broadly available screening test in order to implement improve multi-modal strategy clinical trials. Next generation sequencing (NGS) has begun supplant other technologies genomic profiling. Targeted NGS method that allows parallel thousands short DNA sequences single offering cost-effective approach detecting multiple genetic alterations with minimum amount DNA. In present review, we collected concerning application technology setting cancer.

参考文章(32)
Richard W Tothill, Maria A Doyle, Cliff Meldrum, Next-Generation Sequencing for Cancer Diagnostics: a Practical Perspective The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists. ,vol. 32, pp. 177- 195 ,(2011)
Sing Yu Moorcraft, David Gonzalez, Brian A. Walker, Understanding next generation sequencing in oncology: A guide for oncologists Critical Reviews in Oncology Hematology. ,vol. 96, pp. 463- 474 ,(2015) , 10.1016/J.CRITREVONC.2015.06.007
Stine Aske Danielsen, Peter Wold Eide, Arild Nesbakken, Tormod Guren, Edward Leithe, Ragnhild A. Lothe, Portrait of the PI3K/AKT pathway in colorectal cancer ☆ Biochimica et Biophysica Acta. ,vol. 1855, pp. 104- 121 ,(2015) , 10.1016/J.BBCAN.2014.09.008
Sandy Chevrier, Laurent Arnould, François Ghiringhelli, Bruno Coudert, Pierre Fumoleau, Romain Boidot, Next-generation sequencing analysis of lung and colon carcinomas reveals a variety of genetic alterations. International Journal of Oncology. ,vol. 45, pp. 1167- 1174 ,(2014) , 10.3892/IJO.2014.2528
Bastiaan BJ Tops, Nicola Normanno, Henriette Kurth, Eliana Amato, Andrea Mafficini, Nora Rieber, Delphine Le Corre, Anna Maria Rachiglio, Anne Reiman, Orla Sheils, Christoph Noppen, Ludovic Lacroix, Ian A Cree, Aldo Scarpa, Marjolijn JL Ligtenberg, Pierre Laurent-Puig, Development of a semi-conductor sequencing-based panel for genotyping of colon and lung cancer by the Onconetwork consortium BMC Cancer. ,vol. 15, pp. 26- 26 ,(2015) , 10.1186/S12885-015-1015-5
Sae-Won Han, Hwang-Phill Kim, Jong-Yeon Shin, Eun-Goo Jeong, Won-Chul Lee, Kyung-Hun Lee, Jae-Kyung Won, Tae-Yong Kim, Do-Youn Oh, Seock-Ah Im, Yung-Jue Bang, Seung-Yong Jeong, Kyu Joo Park, Jae-Gahb Park, Gyeong Hoon Kang, Jeong-Sun Seo, Jong-Il Kim, Tae-You Kim, None, Targeted Sequencing of Cancer-Related Genes in Colorectal Cancer Using Next-Generation Sequencing PLOS ONE. ,vol. 8, ,(2013) , 10.1371/JOURNAL.PONE.0064271
Francesca Belardinilli, Carlo Capalbo, Amelia Buffone, Marialaura Petroni, Valeria Colicchia, Sergio Ferraro, Massimo Zani, Arianna Nicolussi, Sonia D'Inzeo, Anna Coppa, Isabella Screpanti, Alberto Gulino, Giuseppe Giannini, Validation of the Ion Torrent PGM sequencing for the prospective routine molecular diagnostic of colorectal cancer. Clinical Biochemistry. ,vol. 48, pp. 908- 910 ,(2015) , 10.1016/J.CLINBIOCHEM.2015.04.003
Catherine E. Cottrell, Hussam Al-Kateb, Andrew J. Bredemeyer, Eric J. Duncavage, David H. Spencer, Haley J. Abel, Christina M. Lockwood, Ian S. Hagemann, Stephanie M. O’Guin, Lauren C. Burcea, Christopher S. Sawyer, Dayna M. Oschwald, Jennifer L. Stratman, Dorie A. Sher, Mark R. Johnson, Justin T. Brown, Paul F. Cliften, Bijoy George, Leslie D. McIntosh, Savita Shrivastava, TuDung T. Nguyen, Jacqueline E. Payton, Mark A. Watson, Seth D. Crosby, Richard D. Head, Robi D. Mitra, Rakesh Nagarajan, Shashikant Kulkarni, Karen Seibert, Herbert W. Virgin, Jeffrey Milbrandt, John D. Pfeifer, Validation of a next-generation sequencing assay for clinical molecular oncology. The Journal of Molecular Diagnostics. ,vol. 16, pp. 89- 105 ,(2014) , 10.1016/J.JMOLDX.2013.10.002
Umberto Malapelle, Elena Vigliar, Roberta Sgariglia, Claudio Bellevicine, Lorenzo Colarossi, Domenico Vitale, Pierlorenzo Pallante, Giancarlo Troncone, Ion Torrent next-generation sequencing for routine identification of clinically relevant mutations in colorectal cancer patients Journal of Clinical Pathology. ,vol. 68, pp. 64- 68 ,(2015) , 10.1136/JCLINPATH-2014-202691
D Veale, T Ashcroft, C Marsh, GJ Gibson, AL Harris, Epidermal growth factor receptors in non-small cell lung cancer. British Journal of Cancer. ,vol. 55, pp. 513- 516 ,(1987) , 10.1038/BJC.1987.104