A receptor for polymerized human and chimpanzee albumins on hepatitis B virus particles co-occurring with HBeAg.

作者: Mitsunobu Imai , Yuko Yanase , Tokuyuki Nojiri , Yuzo Miyakawa , Makoto Mayumi

DOI: 10.1016/0016-5085(79)90328-7

关键词:

摘要: A receptor for polymerized human serum albumin was demonstrated on Dane particles as well 20-nm hepatitis B surface antigen particles, isolated from asymptomatic carriers of virus who were positive HBeAg. In contrast, such not born by obtained antibody to Hepatitis with the heavier than those without, and when treated pronase, they became lighter lost receptor. The is responsible agglutination erythrocytes coated patients Type carriers, which have been attributed autoantibodies directed denatured molecules. When fractions chimpanzees glutaraldehyde, also bound antigen. Polymerized all other experimental animals without susceptibility virus, however, failed bind These results seem suggest a possible role (presently accepted virions) molecules in infecting hepatocytes both humans chimpanzees.

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