Dose adjustment practices among allergists for local reactions to immunotherapy

摘要: Background Dose adjustments for local reactions to immunotherapy have been previously proposed. Several studies shown that systemic from injections are not predicted by previous reactions. However, no reports evaluated the prevalence and rationale of dose adjustment protocols within allergists' practices. Objective To examine response after patients' reaction immunotherapy. Methods On behalf American College Allergy, Asthma Immunology (ACAAI) Immunotherapy Diagnostics Committee, an electronic survey was sent all practicing allergists ACAAI. Participants were asked whether they make behind this decision. Strategies prevent minimize also queried. Results A total 2,797 letters successfully sent, 761 (27.2%) responded survey, with 94.7% participants having completed a fellowship in allergy immunology. Common strategies used included based on injection (79.1%) pretreatment antihistamine (70.1%). Most (91.9%) adjusted these criteria both repeating decreasing size reaction. Rationales beliefs cause discomfort leads patient noncompliance (88.9%), predictive future (45.7%), (29.2%). Conclusions Our results indicate most adjust allergen Although agree reactions, 2 main reasons include concern may lead