Safety of allergen immunotherapy: a review of premedication and dose adjustment

作者: A Erika Morris , Gailen D Marshall

DOI: 10.2217/IMT.12.4

关键词:

摘要: From the first allergen immunotherapy proposed in early 1900s to present day, numerous studies have proven efficacy of for treatment allergic rhinitis, conjunctivitis, asthma and stinging insect hypersensitivity. The major risk, however small, with is anaphylaxis. There has been considerable interest debate regarding risk factors reactions (local systemic) interventions reduce occurrence these reactions. One that especially debated regards dose adjustment various reasons, but particular local In this review, we discuss safety provide a comprehensive review literature schedules doses.

参考文章(27)
Portnoy J, Barnes C, Pacheco F, Bagstad K, Kanarek H, Hall B, Premedication reduces the incidence of systemic reactions during inhalant rush immunotherapy with mixtures of allergenic extracts. Annals of allergy. ,vol. 73, pp. 409- 418 ,(1994)
Christopher M. Webber, Christopher W. Calabria, Assessing the safety of subcutaneous immunotherapy dose adjustments Annals of Allergy Asthma & Immunology. ,vol. 105, pp. 369- 375 ,(2010) , 10.1016/J.ANAI.2010.09.003
David G. Tinkelman, Wilfred Q. Cole, Jane Tunno, Immunotherapy: A one-year prospective study to evaluate risk factors of systemic reactions ☆ ☆☆ ★ The Journal of Allergy and Clinical Immunology. ,vol. 95, pp. 8- 14 ,(1995) , 10.1016/S0091-6749(95)70146-X
Daniel R. More, Larry L. Hagan, Factors affecting compliance with allergen immunotherapy at a military medical center. Annals of Allergy Asthma & Immunology. ,vol. 88, pp. 391- 394 ,(2002) , 10.1016/S1081-1206(10)62370-8
J COHN, A PIZZI, Determinants of patient compliance with allergen immunotherapy The Journal of Allergy and Clinical Immunology. ,vol. 91, pp. 734- 737 ,(1993) , 10.1016/0091-6749(93)90192-I
Stefan Wöhrl, Simon Gamper, Wolfgang Hemmer, Georg Heinze, Georg Stingl, Tamar Kinaciyan, Premedication with montelukast reduces local reactions of allergen immunotherapy. International Archives of Allergy and Immunology. ,vol. 144, pp. 137- 142 ,(2007) , 10.1159/000103225
Christopher W. Calabria, Christopher A. Coop, Michael S. Tankersley, The GILL study: glycerin-induced local reactions in immunotherapy. The Journal of Allergy and Clinical Immunology. ,vol. 121, pp. 222- 226 ,(2008) , 10.1016/J.JACI.2007.08.016
Christopher A. Coop, Michael S. Tankersley, Dose adjustment practices among allergists for local reactions to immunotherapy Annals of Allergy Asthma & Immunology. ,vol. 99, pp. 77- 81 ,(2007) , 10.1016/S1081-1206(10)60625-4