Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster
作者： Michael Dews , Asal Homayouni , Duonan Yu , Danielle Murphy , Cinzia Sevignani
DOI: 10.1038/NG1855
关键词:
摘要: … Both Tsp1 and CTGF are predicted targets for repression by the miR-17-92 microRNA cluster, which was upregulated in colonocytes coexpressing K-Ras and c-Myc. Indeed, miR-17-92 …
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Lynda Chin, Alice Tam, Jason Pomerantz, Michelle Wong, Jocelyn Holash, Nabeel Bardeesy, Qiong Shen, Ronan O'Hagan, Joe Pantginis, Hao Zhou, James W. Horner, Carlos Cordon-Cardo, George D. Yancopoulos, Ronald A. DePinho#, Essential role for oncogenic Ras in tumour maintenance Nature. ,vol. 400, pp. 468- 472 ,(1999) , 10.1038/22788
Aurora Esquela-Kerscher, Frank J. Slack, Oncomirs — microRNAs with a role in cancer Nature Reviews Cancer. ,vol. 6, pp. 259- 269 ,(2006) , 10.1038/NRC1840
Stella Pelengaris, Trevor Littlewood, Michael Khan, George Elia, Gerard Evan, Reversible activation of c-Myc in skin: induction of a complex neoplastic phenotype by a single oncogenic lesion. Molecular Cell. ,vol. 3, pp. 565- 577 ,(1999) , 10.1016/S1097-2765(00)80350-0
Randolph S Watnick, Yi-Ning Cheng, Annapoorni Rangarajan, Tan A Ince, Robert A Weinberg, Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell. ,vol. 3, pp. 219- 231 ,(2003) , 10.1016/S1535-6108(03)00030-8
H-W Hwang, J T Mendell, MicroRNAs in cell proliferation, cell death, and tumorigenesis. British Journal of Cancer. ,vol. 94, pp. 776- 780 ,(2006) , 10.1038/SJ.BJC.6603023
Kathryn A. O'Donnell, Erik A. Wentzel, Karen I. Zeller, Chi V. Dang, Joshua T. Mendell, c-Myc-regulated microRNAs modulate E2F1 expression. Nature. ,vol. 435, pp. 839- 843 ,(2005) , 10.1038/NATURE03677
Richard P. Tucker, The thrombospondin type 1 repeat superfamily. The International Journal of Biochemistry & Cell Biology. ,vol. 36, pp. 969- 974 ,(2004) , 10.1016/J.BIOCEL.2003.12.011
Bruce P Himelstein, Edward J Lee, Hiroshi Sato, Motoharu Seiki, Ruth J Muschel, Transcriptional activation of the matrix metalloproteinase-9 gene in an H-ras and v-myc transformed rat embryo cell line Oncogene. ,vol. 14, pp. 1995- 1998 ,(1997) , 10.1038/SJ.ONC.1201012
C Sevignani, P Wlodarski, J Kirillova, W E Mercer, K G Danielson, R V Iozzo, B Calabretta, Tumorigenic conversion of p53-deficient colon epithelial cells by an activated Ki-ras gene. Journal of Clinical Investigation. ,vol. 101, pp. 1572- 1580 ,(1998) , 10.1172/JCI919
Troy A Baudino, Catriona McKay, Helene Pendeville-Samain, Jonas A Nilsson, Kirsteen H Maclean, Elsie L White, Ann C Davis, James N Ihle, John L Cleveland, c-Myc is essential for vasculogenesis and angiogenesis during development and tumor progression Genes & Development. ,vol. 16, pp. 2530- 2543 ,(2002) , 10.1101/GAD.1024602