Localization of pituitary adenomas by using intraoperative ultrasound in patients with Cushing's disease and no demonstrable pituitary tumor on magnetic resonance imaging.

作者: Joe C. Watson , Thomas H. Shawker , Lynnette K. Nieman , Hetty L. DeVroom , John L. Doppman

DOI: 10.3171/JNS.1998.89.6.0927

关键词:

摘要: Object. Pituitary surgery has been reported to produce remission of Cushing's disease with preservation pituitary function in only 60 70% patients. The inability identify an adenoma accounts for most failed sellar explorations. Most negative surgical explorations occur patients whom magnetic resonance (MR) imaging the demonstrates normal findings, which happens at least 35 45% disease. Methods. To examine usefulness intraoperative ultrasonography (IOUS) identifying no demonstrable tumor (negative findings) on MR imaging, we prospectively assessed results IOUS 68 a (59 patients) or equivocal (nine image from consecutive series 107 (64%). We compared findings and outcomes these group was not availab...

参考文章(23)
C B Wilson, W P Dillon, D Norman, T H Newton, D R Newton, Gd-DTPA-enhanced MR imaging of pituitary adenomas. American Journal of Neuroradiology. ,vol. 10, pp. 949- 954 ,(1989)
Debra J. Devoe, Walter L. Miller, Felix A. Conte, Selna L. Kaplan, Melvin M. Grumbach, Stephen M. Rosenthal, Charles B. Wilson, Stephen E. Gitelman, Long-term outcome in children and adolescents after transsphenoidal surgery for Cushing's disease. The Journal of Clinical Endocrinology and Metabolism. ,vol. 82, pp. 3196- 3202 ,(1997) , 10.1210/JCEM.82.10.4290
John L. Doppman, Joseph A. Frank, Andrew J. Dwyer, Edward H. Oldfield, Donald L. Miller, Lynnette K. Nieman, George P. Chrousos, Gordon B. Cutler, D. Lynn Loriaux, Gadolinium DTPA Enhanced MR Imaging of ACTH-Secreting Microadenomas of the Pituitary Gland Journal of Computer Assisted Tomography. ,vol. 12, pp. 728- 735 ,(1988) , 10.1097/00004728-198809010-00002
Thomas Mindermann, Charles B. Wilson, Pediatric Pituitary Adenomas Neurosurgery. ,vol. 36, pp. 259- 269 ,(1995) , 10.1227/00006123-199502000-00004
Thomas J. Mampalam, Transsphenoidal Microsurgery for Cushing Disease Annals of Internal Medicine. ,vol. 109, pp. 487- 493 ,(1988) , 10.7326/0003-4819-109-6-487
Zvi Ram, Lynnette K. Nieman, Gordon B. Cutler, George P. Chrousos, John L. Doppman, Edward H. Oldfield, Early repeat surgery for persistent Cushing's disease Journal of Neurosurgery. ,vol. 80, pp. 37- 45 ,(1994) , 10.3171/JNS.1994.80.1.0037
J L Doppman, Z Ram, T H Shawker, E H Oldfield, Intraoperative US of the pituitary gland. Work in progress. Radiology. ,vol. 192, pp. 111- 115 ,(1994) , 10.1148/RADIOLOGY.192.1.8208921
Charles B. Wilson, Surgical Management of Pituitary Tumors The Journal of Clinical Endocrinology & Metabolism. ,vol. 82, pp. 2381- 2385 ,(1997) , 10.1210/JCEM.82.8.4188