Exploitation of sulfated glycosaminoglycan status for precision medicine of platinums in triple-negative breast cancer
Litovchick L , Takabe K , Takabe K , Alzubi Ma
bioRxiv
2021
MYCN-amplified neuroblastoma is addicted to iron and vulnerable to inhibition of the system Xc-/glutathione axis
Anthony C. Faber , Bin Hu , Sosipatros A. Boikos , Jennifer E. Koblinski
Cancer Research 81 ( 7) 1896 -1908
1
2021
Targeting transcription of MCL-1 sensitizes HER2-amplified breast cancers to HER2 inhibitors.
Maurizio Scaltriti , Maurizio Scaltriti , Anthony C. Faber , Bin Hu
Cell Death and Disease 12 ( 2) 1 -13
2021
Catastrophic ATP loss underlies a metabolic combination therapy tailored for MYCN -amplified neuroblastoma.
Cyril H Benes , Timothy L Lochmann , Patricia Greninger , Anthony C Faber
Proceedings of the National Academy of Sciences of the United States of America 118 ( 13)
2021
Unmasking BCL-2 Addiction in Synovial Sarcoma by Overcoming Low NOXA.
Hiromichi Ebi , Naoko Takebe , Steven C. Smith , Hisashi Harada
Cancers 13 ( 10) 2310
2021
Venetoclax-based rational combinations are effective in models of MYCN-amplified neuroblastoma.
Yaël P Mossé , Cyril H Benes , Patricia Greninger , Renata Sano
Molecular Cancer Therapeutics
2021
In vivo modeling of malignant glioma: the road to effective therapy.
Timothy P. Kegelman , Bin Hu , Luni Emdad , Swadesh K. Das
Advances in Cancer Research 121 261 -330
19
2014
Selected Approaches for Rational Drug Design and High Throughput Screening to Identify Anti-Cancer Molecules
Michael Hedvat , Luni Emdad , Swadesh K. Das , Keetae Kim
Anti-cancer Agents in Medicinal Chemistry 12 ( 9) 1143 -1155
29
2012
Astrocyte Elevated Gene-1 Regulates β-Catenin Signaling to Maintain Glioma Stem-like Stemness and Self-Renewal.
Bin Hu , Luni Emdad , Timothy P. Kegelman , Xue-Ning Shen
Molecular Cancer Research 15 ( 2) 225 -233
14
2017
Evaluation of combined BCL-2/MCL-1 inhibition as a therapeutic approach for synovial sarcoma.
Carter Kent Fairchild , Konstantinos Floros , Sheeba Jacob , Colin Coon
Journal of Clinical Oncology 38 ( 15_suppl) e23561 -e23561
1
2020
Suppression of miR-184 in malignant gliomas upregulates SND1 and promotes tumor aggressiveness
Luni Emdad , Aleksandar Janjic , Mohammad A. Alzubi , Bin Hu
Neuro-oncology 17 ( 3) 419 -429
51
2015
Abstract PO-024: Catastrophic ATP loss underlines a metabolic combination therapy tailored for MYCN-amplified neuroblastoma
Krista M. Powell , Timonthy L. Lochmann , Konstantinos V. Floros , Marissa L. Calbert
Cancer Research 80
2020
The proteoglycan brevican binds to fibronectin after proteolytic cleavage and promotes glioma cell motility
Bin Hu , Leopold L. Kong , Russell T. Matthews , Mariano S. Viapiano
Journal of Biological Chemistry 283 ( 36) 24848 -24859
116
2008
Targeting tumor invasion: the roles of MDA-9/Syntenin.
Timothy P Kegelman , Swadesh K Das , Luni Emdad , Bin Hu
Expert Opinion on Therapeutic Targets 19 ( 1) 97 -112
36
2015
AEG-1-AKT2: A novel complex controlling the aggressiveness of glioblastoma.
Luni Emdad , Bin Hu , Swadesh K Das , Devanand Sarkar
Molecular and Cellular Oncology 2 ( 3)
7
2015
Telomestatin Impairs Glioma Stem Cell Survival and Growth through the Disruption of Telomeric G-Quadruplex and Inhibition of the Proto-oncogene, c-Myb
Takeshi Miyazaki , Yang Pan , Kaushal Joshi , Deepti Purohit
Clinical Cancer Research 18 ( 5) 1268 -1280
80
2012
Sorting Nexin 5 Controls Head and Neck Squamous Cell Carcinoma Progression by Modulating FBW7.
Jinyang Cai , Ming Sun , Bin Hu , Brad Windle
Journal of Cancer 10 ( 13) 2942 -2952
5
2019
Fibulin-3 is uniquely upregulated in malignant gliomas and promotes tumor cell motility and invasion.
Bin Hu , Keerthi K. Thirtamara-Rajamani , Hosung Sim , Mariano S. Viapiano
Molecular Cancer Research 7 ( 11) 1756 -1770
97
2009
Astrocyte elevated gene-1 interacts with Akt isoform 2 to control glioma growth, survival, and pathogenesis.
Bin Hu , Luni Emdad , Manny D. Bacolod , Timothy P. Kegelman
Cancer Research 74 ( 24) 7321 -7332
43
2014
Novel paracrine modulation of Notch-DLL4 signaling by fibulin-3 promotes angiogenesis in high-grade gliomas
Mohan S Nandhu , Bin Hu , Susan E Cole , Anat Erdreich-Epstein
Cancer Research 74 ( 19) 5435 -5448
24
2014