Modulation of antioxidant, chelating and antimicrobial activity of poplar chemo-type propolis by extraction procures
作者： Mario Jug , Marijana Zovko Končić , Ivan Kosalec
DOI: 10.1016/J.LWT.2014.02.006
关键词: Propolis 、 Maceration (wine) 、 Chelation 、 Antioxidant 、 Candida albicans 、 Antimicrobial 、 Chromatography 、 Streptococcus mutans 、 Chemistry 、 Extraction (chemistry)
摘要: Abstract This investigation was aimed to prepare solid propolis extracts by lyophilisation and evaluate the efficiency of different extraction procedures (maceration/ultrasound extraction) types media used on phenolic compounds (TP), flavonoids (TF) acids (TPA) from raw poplar type propolis. Obtained lyophilised were evaluated in terms yield, antioxidant potential antimicrobial activity against selected bacterial/fungal stains. Those parameters varied significantly as a function applied. In this regard, 80% ethanol found be preferred medium, allowing efficient TP TF with high yields. The resulting notable radical scavengers showing antibacterial Streptococcus mutans but less Pseudomonas aeruginosa . Also, moderate antifungal Candida albicans observed. On contrary, prepared aqueous showed poor tested stains active Fe 2+ chelators. Ultrasound comparable maceration bioactive propolis, offered additional advantages ensuring at rather low temperature (4 °C vs. 25/50 °C for maceration) short time (30 min 24 h maceration).
irb.hr
elsevier.com
sci-hub.se 参考文章(32)
Jean-Baptiste Galey, Potential Use of Iron Chelators against Oxidative Damage Advances in pharmacology. ,vol. 38, pp. 167- 203 ,(1996) , 10.1016/S1054-3589(08)60984-9
Vernon L. Singleton, Rudolf Orthofer, Rosa M. Lamuela-Raventós, ANALYSIS OF TOTAL PHENOLS AND OTHER OXIDATION SUBSTRATES AND ANTIOXIDANTS BY MEANS OF FOLIN-CIOCALTEU REAGENT Methods in Enzymology. ,vol. 299, pp. 152- 178 ,(1999) , 10.1016/S0076-6879(99)99017-1
Idenize Barbosa da Silva Cunha, Maria Lucia Tiveron Rodrigues, Eduardo Cesar Meurer, Vassia S Bankova, Maria Cristina Marcucci, Marcos Nogueira Eberlin, Alexandra Christine Helena Frankland Sawaya, None, Effect of the maceration time on chemical composition of extracts of Brazilian propolis Journal of Apicultural Research. ,vol. 45, pp. 137- 144 ,(2006) , 10.1080/00218839.2006.11101332
Zeki Yildirim, Süleyman Hacievliyagil, Nurettin Onur Kutlu, Nasuhi Engin Aydin, Mine Kurkcuoglu, Mustafa Iraz, Riza Durmaz, None, Effect of water extract of Turkish propolis on tuberculosis infection in guinea-pigs. Pharmacological Research. ,vol. 49, pp. 287- 292 ,(2004) , 10.1016/J.PHRS.2003.10.007
Zrinka Rajić, Marijana Končić, Kristina Miloloža, Ivana Perković, Ivan Butula, Franz Bucar, Branka Zorc, Primaquine-NSAID twin drugs: Synthesis, radical scavenging, antioxidant and Fe2+ chelating activity Acta Pharmaceutica. ,vol. 60, pp. 325- 337 ,(2010) , 10.2478/V10007-010-0024-9
Gülhan Vardar-Ünlü, Sibel Silici, Mehmet Ünlü, Composition and in vitro antimicrobial activity of Populus buds and poplar-type propolis World Journal of Microbiology & Biotechnology. ,vol. 24, pp. 1011- 1017 ,(2008) , 10.1007/S11274-007-9566-5
Cengiz Sarikurkcu, Kadir Arisoy, Bektas Tepe, Ahmet Cakir, Gulsah Abali, Ebru Mete, Studies on the antioxidant activity of essential oil and different solvent extracts of Vitex agnus castus L. fruits from Turkey Food and Chemical Toxicology. ,vol. 47, pp. 2479- 2483 ,(2009) , 10.1016/J.FCT.2009.07.005
R. Amarowicz, R.B. Pegg, P. Rahimi-Moghaddam, B. Barl, J.A. Weil, Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies Food Chemistry. ,vol. 84, pp. 551- 562 ,(2004) , 10.1016/S0308-8146(03)00278-4
Shigenori Kumazawa, Tomoko Hamasaka, Tsutomu Nakayama, Antioxidant activity of propolis of various geographic origins Food Chemistry. ,vol. 84, pp. 329- 339 ,(2004) , 10.1016/S0308-8146(03)00216-4
Aldona Dembinska-Kiec, Otto Mykkänen, Beata Kiec-Wilk, Hannu Mykkänen, Antioxidant phytochemicals against type 2 diabetes. British Journal of Nutrition. ,vol. 99, ,(2008) , 10.1017/S000711450896579X