作者: F Chang , J T Lee , P M Navolanic , L S Steelman , J G Shelton
关键词: PTEN 、 Cell biology 、 Biology 、 Cancer research 、 Protein kinase B 、 Malignant transformation 、 PI3K/AKT/mTOR pathway 、 Neoplastic transformation 、 Signal transduction 、 Carcinogenesis 、 Cell cycle
摘要: … that the PI3K/Akt pathway is a viable target for novel antineoplastic drugs. This review will describe PI3K/Akt pathway signaling and its effects on cell cycle progression, prevention of …