BRAF screening as a low-cost effective strategy for simplifying HNPCC genetic testing
作者： E Domingo , P Laiho , M Ollikainen , M Pinto , L Wang
关键词: Genetic testing 、 Germline mutation 、 MLH1 、 Cancer research 、 Amsterdam criteria 、 Genetics 、 Microsatellite instability 、 V600E 、 MSH2 、 Genetic counseling 、 Medicine 、 Genetics(clinical)
摘要: … The most effective strategy for the diagnosis of HNPCC is the compilation of a thorough family history of colorectal cancer and fulfilment of the Amsterdam criteria. However, this …
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