A tracking algorithm for cell motility assays in CMOS systems
作者： C. Martinez-Gomez , A. Olmo , G. Huertas , P. Perez , A. Maldonado-Jacobi
DOI: 10.1109/EMBC.2017.8036954
关键词: Motility 、 Cell 、 Cancer cell 、 Computer science 、 Path (graph theory) 、 Center of mass 、 Brownian motion 、 CMOS 、 Cell Motility Assays 、 Cancer 、 Fluorescence 、 Electrode 、 Matrix (mathematics) 、 Tracking (particle physics) 、 Algorithm
摘要: This work proposes a method for the study and real-time monitoring of single cell on 2D electrode matrix, great interest in motility assays characterization cancer metastasis. A CMOS system proposal location based occupation maps data generated from Electrical Cell-substrate Impedance Spectroscopy (ECIS) has been developed. From experimental data, an algorithm analysis eight nearest neighbours implemented to find center mass. The path followed by cell, proposing Brownian route, simulated with proposed algorithm. presented results give accuracy over 95% determination coordinates (x, y) expected
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