Cellular immune response in the small intestine of two broiler chicken lines orally inoculated with malabsorption syndrome homogenates.

摘要: Abstract We studied the cellular immune response against malabsorption syndrome (MAS) in two broiler chicken lines, A and B. determined number of pan T-lymphocytes (CD3), helper (CD4), cytotoxic (CD8) macrophages/monocytes small intestine first 2 weeks after oral inoculation MAS homogenates, MAS80 MAS97-1. The cells were detected on cryostat tissue by immunohistochemistry counted villus area. In trial 1, we compared lines for weight gain depression, intestinal lesion CD3, CD4, CD8 inoculation. Although there was no significant difference depression between line B had significantly higher numbers CD8+ T-cells per area than A. To confirm part results done which different homogenates Broiler orally inoculated with either MAS97-1, homogenate obtained from healthy chickens (healthy homogenate), or phosphate buffered saline (PBS). this trial, MAS97-1 also induced lesions, whereas “healthy homogenate” PBS did not induce lesions. broilers more PBS. Increased affected intestines suggests an increase T-cell activity.