Immediate Hypersensitivity Reactions Induced by Triamcinolone in a Patient with Atopic Dermatitis.

作者: Jee Hee Son , Sook Young Park , Yong Se Cho , Bo Young Chung , Hye One Kim

DOI: 10.3346/JKMS.2018.33.E87

关键词:

摘要: Corticosteroids are potent anti-inflammatory and anti-allergic agents used in the treatment of various inflammatory diseases, including allergic disease. They frequently considered therapy-of-choice for many skin diseases. However, reactions caused by corticosteroids have been reported. Among these, delayed to topical steroids more common, whereas immediate systemic rare. Herein, we report case a 32-year-old woman with triamcinolone-induced hypersensitivity reaction, which patient had positive prick test result triamcinolone. She has atopic dermatitis (AD) three years. steroid, cyclosporine, antihistamine AD. In clinic, approximately 10 minutes after intralesional injection triamcinolone, she complained erythematous patches slight elevation itching on face, trunk, both hands. After intravenous dexamethasone, her symptoms got worse. epinephrine, all resolved within two hours. We performed an open test. only from triamcinolone; other showed negative results tests. Dermatologists should be aware possibility anaphylaxis or response corticosteroids.

参考文章(17)
A. Aranda, C. Mayorga, A. Ariza, I. Doña, N. Blanca-Lopez, G. Canto, M. Blanca, M. J. Torres, IgE‐mediated hypersensitivity reactions to methylprednisolone Allergy. ,vol. 65, pp. 1376- 1380 ,(2010) , 10.1111/J.1398-9995.2010.02386.X
Malene Knarborg, Elisabeth Bendstrup, Ole Hilberg, Increasing awareness of corticosteroid hypersensitivity reactions is important Respirology case reports. ,vol. 1, pp. 43- 45 ,(2013) , 10.1002/RCR2.13
Adesh Patel, Sami L. Bahna, Immediate hypersensitivity reactions to corticosteroids. Annals of Allergy Asthma & Immunology. ,vol. 115, pp. 178- 182 ,(2015) , 10.1016/J.ANAI.2015.06.022
Jung Eun Kim, Hyun Jeong Kim, Bark-Lynn Lew, Kyung Ho Lee, Seung Phil Hong, Yong Hyun Jang, Kui Young Park, Seong Jun Seo, Jung Min Bae, Eung Ho Choi, Ki Beom Suhr, Seung Chul Lee, Hyun Chang Ko, Young Lip Park, Sang Wook Son, Young Jun Seo, Yang Won Lee, Sang Hyun Cho, Chun Wook Park, Joo Young Roh, Consensus Guidelines for the Treatment of Atopic Dermatitis in Korea (Part II): Systemic Treatment. Annals of Dermatology. ,vol. 27, pp. 578- 592 ,(2015) , 10.5021/AD.2015.27.5.578
M. Baeck, L. Marot, J.-F. Nicolas, C. Pilette, D. Tennstedt, A. Goossens, Allergic hypersensitivity to topical and systemic corticosteroids: a review. Allergy. ,vol. 64, pp. 978- 994 ,(2009) , 10.1111/J.1398-9995.2009.02038.X
Howard I. Maibach, Contact Urticaria Syndrome ,(1997)
Eva Helaskoski, Outi Kuuliala, Kristiina Aalto-Korte, Occupational contact urticaria caused by cyclic acid anhydrides. Contact Dermatitis. ,vol. 60, pp. 214- 221 ,(2009) , 10.1111/J.1600-0536.2009.01526.X
Basem M. Dajani, Naif A. Sliman, Kandil S. Shubair, Yousef S. Hamzeh, Bronchospasm caused by intravenous hydrocortisone sodium succinate (Solu-Cortef) in aspirin-sensitive asthmatics. The Journal of Allergy and Clinical Immunology. ,vol. 68, pp. 201- 204 ,(1981) , 10.1016/0091-6749(81)90184-6
Robert L. Rietschel, Contact dermatitis and diagnostic techniques. Allergy and Asthma Proceedings. ,vol. 10, pp. 403- 411 ,(1989) , 10.2500/108854189778935782