Effects of insulin replacement on ejaculatory dysfunction in streptozotocin-induced diabetic rats

摘要: Objectives:  To investigate the effects of insulin replacement on ejaculatory dysfunction in streptozotocin (STZ)-induced diabetic rats. Methods:  Rats were divided into three groups: (i) STZ-treated group; (ii) + (5 and 2 international units [IU]) (iii) control group. The function rats was evaluated using spontaneous seminal emission (SSE) test. amount vesicle fluid (SVF) stored measured after SSE Blood glucose a simplified blood meter. Results:  In test, capacity STZ-induced deteriorated with time onset diabetes, incidence ejaculated material (SM) significantly decreased from 5 weeks STZ administration. Likewise, SVF also time-dependent manner. One week administration when had not yet diminished, (for 4 weeks) completely prevented decrease frequency SSE, SM SVF. However, occurred or 15 weeks administration) did allow all parameters for to be restored levels group. Conclusion:  This study demonstrates that at an early stage following can prevent rats, but once occurs, treatment alone does restore normal levels. addition, this suggests loss results may involved mechanism rats.