Impaired regulation of corticosterone levels during fasting in aging rats.
作者： Gary W. Britton , Samuel Rotenberg , Richard C. Adelman
DOI: 10.1016/0006-291X(75)90236-3
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摘要: Abstract The concentration of corticosterone in aortal blood 3-day fasted rats decreases approximately 75% between 2- and 24-months age. reduced level hormone aging is not attributable to an enhanced rate utilization from the or a diminished steroidogenic capacity adrenal cortex, but apparently reflects deficiency extraadrenal regulatory mechanisms.
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sci-hub.se 参考文章(11)
Richard C. Adelman, An age-dependent modification of enzyme regulation. Journal of Biological Chemistry. ,vol. 245, pp. 1032- 1035 ,(1970) , 10.1016/S0021-9258(18)63285-5
V.V. Frolkis, N.V. Verzhikovskaya, G.V. Valueva, The thyroid and age. Experimental Gerontology. ,vol. 8, pp. 285- 296 ,(1973) , 10.1016/0531-5565(73)90041-7
V. Hainer, V. Kubik, L. Krulich, S. Stoilov, Plasma corticosterone changes in starved rats: effect of thyroidectomy. Hormone and Metabolic Research. ,vol. 4, pp. 314- 315 ,(2009) , 10.1055/S-0028-1097101
R. C. ADELMAN, C. FREEMAN, Age-dependent regulation of glucokinase and tyrosine aminotransferase activities of rat liver in vivo by adrenal, pancreatic and pituitary hormones. Endocrinology. ,vol. 90, pp. 1551- 1560 ,(1972) , 10.1210/ENDO-90-6-1551
DOROTHY T. KRIEGER, Glandular End Organ Deficiency Associated with Secretion of Biologically Inactive Pituitary Peptides The Journal of Clinical Endocrinology and Metabolism. ,vol. 38, pp. 964- 975 ,(1974) , 10.1210/JCEM-38-6-964
RICHARD C. ADELMAN, Reappraisal of Biological Ageing Nature. ,vol. 228, pp. 1095- 1096 ,(1970) , 10.1038/2281095A0
C. S. Pittendrigh, S. Daan, Circadian oscillations in rodents : A systematic increase of their frequency with age Science. ,vol. 186, pp. 548- 550 ,(1974) , 10.1126/SCIENCE.186.4163.548
Caleb E. Finch, Jeffrey R. Foster, Alfred E. Mirsky, Ageing and the Regulation of Cell Activities during Exposure to Cold The Journal of General Physiology. ,vol. 54, pp. 690- 712 ,(1969) , 10.1085/JGP.54.6.690
Abbas E. Kitabchi, Louise C. Kitchell, A simplified fluorometric method for determination of blood cortisol using phase-separating filter paper. Analytical Biochemistry. ,vol. 34, pp. 529- 537 ,(1970) , 10.1016/0003-2697(70)90138-7
W D Denckla, Role of the pituitary and thyroid glands in the decline of minimal O2 consumption with age. Journal of Clinical Investigation. ,vol. 53, pp. 572- 581 ,(1974) , 10.1172/JCI107592