Ordering of mouse immunoglobulin heavy chain genes by molecular cloning.
作者： Akira Shimizu , Naoki Takahashi , Yuriko Yamawaki-Kataoka , Yasuyoshi Nishida , Tohru Kataoka
DOI: 10.1038/289149A0
关键词:
摘要: We have determined the order of mouse immunoglobulin γ1 γ2b, γ2a and ɛ genes by molecular cloning overlapping chromosomal segments. The results clearly demonstrate that is 5′–γ1–(21 kilobases)–γ2b–(15 kilobases)–γ2a–(15 kilobases)–ɛ–3′. There seem to be no J regions at 5′ side each constant region gene so far obtained except for μ these repetitive sequences characteristic switch (S) their side.
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