Role of nitric oxide in angiogenesis and microcirculation in tumors.

作者: Dai Fukumura , Rakesh K. Jain

DOI: 10.1023/A:1005908805527

关键词:

摘要: … tumor angiogenesis; 2) endogenous NO derived from tumor vascular endothelium and/or tumor cells increases and/or maintains tumor … exogenous NO can increase tumor blood flow via …

参考文章(67)
Y. Yuan, H. J. Granger, D. C. Zawieja, D. V. DeFily, W. M. Chilian, Histamine increases venular permeability via a phospholipase C-NO synthase-guanylate cyclase cascade American Journal of Physiology-heart and Circulatory Physiology. ,vol. 264, ,(1993) , 10.1152/AJPHEART.1993.264.5.H1734
Franklin H. Epstein, Salvador Moncada, Annie Higgs, The L-Arginine-Nitric Oxide Pathway The New England Journal of Medicine. ,vol. 329, pp. 2002- 2012 ,(1993) , 10.1056/NEJM199312303292706
Jason S. Hahn, Rod D. Braun, Mark W. Dewhirst, Siqing Shan, Stacey A. Snyder, Janis M. Taube, Edgardo T. Ong, Gary L. Rosner, Richard K. Dodge, Joseph Bonaventura, Celia Bonaventura, Joseph DeAngelo, Robert E. Meyer, Stroma-Free Human Hemoglobin A Decreases R3230Ac Rat Mammary Adenocarcinoma Blood Flow and Oxygen Partial Pressure Radiation Research. ,vol. 147, pp. 185- 194 ,(1997) , 10.2307/3579420
L. Morbidelli, C. H. Chang, J. G. Douglas, H. J. Granger, F. Ledda, M. Ziche, Nitric oxide mediates mitogenic effect of VEGF on coronary venular endothelium American Journal of Physiology-heart and Circulatory Physiology. ,vol. 270, ,(1996) , 10.1152/AJPHEART.1996.270.1.H411
H. M. Wu, Q. Huang, Y. Yuan, H. J. Granger, VEGF induces NO-dependent hyperpermeability in coronary venules. American Journal of Physiology-heart and Circulatory Physiology. ,vol. 271, ,(1996) , 10.1152/AJPHEART.1996.271.6.H2735
M. Detmar, A. M. Dvorak, L. F. Brown, H. F. Dvorak, Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis. American Journal of Pathology. ,vol. 146, pp. 1029- 1039 ,(1995)
A. Holzmann, K. D. Bloch, L. S. Sanchez, G. Filippov, W. M. Zapol, Hyporesponsiveness to inhaled nitric oxide in isolated, perfused lungs from endotoxin-challenged rats. American Journal of Physiology-lung Cellular and Molecular Physiology. ,vol. 271, ,(1996) , 10.1152/AJPLUNG.1996.271.6.L981
Robert J. Melder, Gerald C. Koenig, Brian P. Witwer, Nina Safabakhsh, Lance L. Munn, Rakesh K. Jain, During angiogenesis, vascular endothelial growth factor and basic fibroblast growth factor regulate natural killer cell adhesion to tumor endothelium. Nature Medicine. ,vol. 2, pp. 992- 997 ,(1996) , 10.1038/NM0996-992
Vivien E. Prise, David J. Chaplin, Gillian M. Tozer, Inhibition of nitric oxide synthase induces a selective reduction in tumor blood flow that is reversible with L-arginine. Cancer Research. ,vol. 57, pp. 948- 955 ,(1997)
Koichiro Matsukado, Keith L. Black, Shin Nakano, Increased Brain Tumor Microvessel Permeability after Intracarotid Bradykinin Infusion Is Mediated by Nitric Oxide Cancer Research. ,vol. 56, pp. 4027- 4031 ,(1996)