Marked elevation of vascular endothelial growth factor and basic fibroblast growth factor in pericardial fluid of patients with angina pectoris.
作者： Masatoshi Fujita , Masaki Ikemoto , Terumitsu Tanaka , Shun-ichi Tamaki , Ario Yamazato
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摘要: Although we reported that basic fibroblast growth factor (bFGF) levels in pericardial fluid of patients with unstable angina are apparently increased, it was unclear whether vascular endothelial (VEGF) is also increased myocardial ischemia. Using an enzyme-linked immunosorbent assay, measured the concentrations VEGF and bFGF 51 open heart surgery. Patients were divided into group A (n=10) class III (Braunwald's classification), B (n=24) I or II stable C (n=17) non-ischemic disease. The level 83+/-7 pg/ml, being significantly (p<0.001) higher than 27+/-3 pg/ml 28+/-5 C. groups 1461+/-579 1224+/-161 respectively, (p<0.05) 292+/-97 only severe rest within 2 days before emergency coronary artery bypass graft surgery (CABG), while all undergoing CABG for Thus may play important roles mediating collateral humans.
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K. Peter Rentrop, Marc Cohen, Heiner Blanke, Robert A. Phillips, Changes in collateral channel filling immediately after controlled coronary artery occlusion by an angioplasty balloon in human subjects Journal of the American College of Cardiology. ,vol. 5, pp. 587- 592 ,(1985) , 10.1016/S0735-1097(85)80380-6
S Sasayama, M Fujita, Recent insights into coronary collateral circulation. Circulation. ,vol. 85, pp. 1197- 1204 ,(1992) , 10.1161/01.CIR.85.3.1197
Masatoshi Fujita, Masaki Ikemoto, Masamichi Kishishita, Hideo Otani, Ryuji Nohara, Terumitsu Tanaka, Shun-ichi Tamaki, Ario Yamazato, Shigetake Sasayama, Elevated Basic Fibroblast Growth Factor in Pericardial Fluid of Patients With Unstable Angina Circulation. ,vol. 94, pp. 610- 613 ,(1996) , 10.1161/01.CIR.94.4.610
Anthony Jackson, Francesca Tarantini, Susan Gamble, Stanley Friedman, Thomas Maciag, The Release of Fibroblast Growth Factor-1 from NIH 3T3 Cells in Response to Temperature Involves the Function of Cysteine Residues Journal of Biological Chemistry. ,vol. 270, pp. 33- 36 ,(1995) , 10.1074/JBC.270.1.33
E Brogi, T Wu, A Namiki, J M Isner, Indirect angiogenic cytokines upregulate VEGF and bFGF gene expression in vascular smooth muscle cells, whereas hypoxia upregulates VEGF expression only Circulation. ,vol. 90, pp. 649- 652 ,(1994) , 10.1161/01.CIR.90.2.649
Masatoshi Fujita, Salutary effects of myocardial ischemia in coronary artery disease International Journal of Cardiology. ,vol. 52, pp. 197- 202 ,(1995) , 10.1016/0167-5273(95)02477-8
J D Symons, K F Pitsillides, J C Longhurst, Chronic reduction of myocardial ischemia does not attenuate coronary collateral development in miniswine. Circulation. ,vol. 86, pp. 660- 671 ,(1992) , 10.1161/01.CIR.86.2.660
E Braunwald, Unstable angina : a classification Circulation. ,vol. 80, pp. 410- 414 ,(1989) , 10.1161/01.CIR.80.2.410
Takayuki Asahara, Christophe Bauters, Lu P Zheng, Satoshi Takeshita, Stuart Bunting, Napoleone Ferrara, James F Symes, Jeffrey M Isner, None, Synergistic Effect of Vascular Endothelial Growth Factor and Basic Fibroblast Growth Factor on Angiogenesis In Vivo Circulation. ,vol. 92, pp. 365- 371 ,(1995) , 10.1161/01.CIR.92.9.365
Robert W. Thompson, Giles F. Whalen, Kim B. Saunders, Thomas Hores, Patricia A. D'Amore, Heparin-mediated release of fibroblast growth factor-like activity into the circulation of rabbits. Growth Factors Journal. ,vol. 3, pp. 221- 229 ,(1990) , 10.3109/08977199009043906