Gemistocytic astrocytomas: histomorphology, proliferative potential and genetic alterations – a study of 32 cases
作者： Singh Avninder , Mehar Chand Sharma , Prabal Deb , Veer Singh Mehta , Asish Kumar Karak
DOI: 10.1007/S11060-005-9077-X
关键词:
摘要: Gemistocytic astrocytomas (GAs) are a distinct variant of astrocytomas, generally classified as WHO grade II, and associated with an aggressive biological behavior. This study was undertaken to determine the histomorphological spectrum, correlate these their proliferative potential genetic alterations, in order establish basis for unfavorable prognosis.
springer.com
sci-hub.se 参考文章(23)
Takashi Tamiya, Shinichiro Mizumatsu, Yasuhiro Ono, Tomoyasu Abe, Kengo Matsumoto, Tomohisa Furuta, Takashi Ohmoto, High cyclin E/low p27Kip1 expression is associated with poor prognosis in astrocytomas. Acta Neuropathologica. ,vol. 101, pp. 334- 340 ,(2001) , 10.1007/S004010000261
J Takeuchi, R O Barnard, Perivascular lymphocytic cuffing in astrocytomas Acta Neuropathologica. ,vol. 35, pp. 265- 271 ,(1976)
H Ohgaki, K Watanabe, Y Yonekawa, O Tachibana, P Kleihues, Role of gemistocytes in astrocytoma progression. Laboratory Investigation. ,vol. 76, pp. 277- 284 ,(1997)
Rui M Reis, Akira Hara, Paul Kleihues, Hiroko Ohgaki, None, Genetic evidence of the neoplastic nature of gemistocytes in astrocytomas. Acta Neuropathologica. ,vol. 102, pp. 422- 425 ,(2001) , 10.1007/S004010100452
Paul Kleihues, David N. Louis, Bernd W. Scheithauer, Lucy B. Rorke, Guido Reifenberger, Peter C. Burger, Webster K. Cavenee, The WHO Classification of Tumors of the Nervous System Journal of Neuropathology and Experimental Neurology. ,vol. 61, pp. 215- 225 ,(2002) , 10.1093/JNEN/61.3.215
David N. Louis, The p53 gene and protein in human brain tumors. Journal of Neuropathology and Experimental Neurology. ,vol. 53, pp. 11- 21 ,(1994) , 10.1097/00005072-199401000-00002
P. Cavalla, A. Dutto, R. Piva, P. Richiardi, R. Grosso, D. Schiffer, Cyclin D1 expression in gliomas. Acta Neuropathologica. ,vol. 95, pp. 131- 135 ,(1998) , 10.1007/S004010050776
B. Giometto, F. Bozza, F. Faresin, L. Alessio, S. Mingrino, B. Tavolato, Immune infiltrates and cytokines in gliomas Acta Neurochirurgica. ,vol. 138, pp. 50- 56 ,(1996) , 10.1007/BF01411724
Kunihiko Watanabe, Aurelia Peraud, Catherine Gratas, Susumu Wakai, Paul Kleihues, H. Ohgaki, p53 and PTEN gene mutations in gemistocytic astrocytomas. Acta Neuropathologica. ,vol. 95, pp. 559- 564 ,(1998) , 10.1007/S004010050840
W. Roggendorf, S. Strupp, W. Paulus, Distribution and characterization of microglia/macrophages in human brain tumors Acta Neuropathologica. ,vol. 92, pp. 288- 293 ,(1996) , 10.1007/S004010050520