Cell proliferation after ischemic infarction in gerbil brain
作者： Monica Du Bois , Phillip D. Bowman , Gary W. Goldstein
DOI: 10.1016/0006-8993(85)90183-0
关键词:
摘要: In order to study cell proliferation after ischemic infarction, a model of bilateral common carotid artery occlusion in the gerbil was developed. A comparison survival rates 15, 30, 45 and 60 min revealed that maximum duration ischemia which most (72%) gerbils were alive at 1 week. The administration pentobarbital (single dose, 30 mg/kg) postoperatively badly seizing animals increased 100%. Large, well-demarcated infarcts present posterior thalamus or midbrain 62% subjected occlusion. 60% these unilateral; 40% they bilateral. To quantitate from 12 h 25 days ischemia, injected with [3H]thymidine 4 prior sacrifice, autoradiographs prepared sectioned brains. Proliferation took place 2 7 occlusion, 24% labeled cells 6 days.
core.ac.uk
elsevier.com
sci-hub.se 参考文章(41)
P. A. Cancilla, L. E. DeBault, Freeze Injury and Repair of Cerebral Microvessels Advances in Experimental Medicine and Biology. ,vol. 131, pp. 257- 269 ,(1980) , 10.1007/978-1-4684-3752-2_20
Cavanagh Jb, The proliferation of astrocytes around a needle wound in the rat brain. Journal of Anatomy. ,vol. 106, pp. 471- 487 ,(1970)
H M Baum, M Robins, The National Survey of Stroke. Incidence. Stroke. ,vol. 12, ,(1981)
Lennart Persson, Cellular reactions to small cerebral stab wounds in the rat frontal lobe Virchows Archiv B Cell Pathology. ,vol. 22, pp. 21- 37 ,(1976) , 10.1007/BF02889204
D Gospodarowicz, Purification of a fibroblast growth factor from bovine pituitary. Journal of Biological Chemistry. ,vol. 250, pp. 2515- 2520 ,(1975) , 10.1016/S0021-9258(19)41631-1
B. B. Mršulja, B. J. Mršulja, M. Spatz, U. Ito, J. T. Walker, I. Klatzo, Experimental cerebral ischemia in Mongolian gerbils. IV. Behaviour of biogenic amines. Acta Neuropathologica. ,vol. 36, pp. 1- 8 ,(1976) , 10.1007/BF00685142
T Maciag, G A Hoover, R Weinstein, High and low molecular weight forms of endothelial cell growth factor. Journal of Biological Chemistry. ,vol. 257, pp. 5333- 5336 ,(1982) , 10.1016/S0021-9258(19)83778-X
Ronald F. Dodson, Lena W.-F. Chu, K.M.A. Welch, V.S. Achar, Acute tissue response to cerebral ischemia in the gerbil Journal of the Neurological Sciences. ,vol. 33, pp. 161- 170 ,(1977) , 10.1016/0022-510X(77)90190-3
Norman Latov, Gajanan Nilaver, Earl A. Zimmerman, William G. Johnson, Ann-Judith Silverman, Richard Defendini, Lucien Cote, Fibrillary astrocytes proliferate in response to brain injury: A study combining immunoperoxidase technique for glial fibrillary acidic protein and radioautography of tritiated thymidine Developmental Biology. ,vol. 72, pp. 381- 384 ,(1979) , 10.1016/0012-1606(79)90127-1
Konstantin-Alexander Hossmann, Volker Zimmermann, Resuscitation of the monkey brain after 1 h complete ischemia. I. Physiological and morphological observations. Brain Research. ,vol. 81, pp. 59- 74 ,(1974) , 10.1016/0006-8993(74)90478-8