BRCA1 mutations in primary breast and ovarian carcinomas
作者： P Andrew Futreal , Qingyun Liu , Donna Shattuck-Eidens , Charles Cochran , Keith Harshman
关键词:
摘要: Loss of heterozygosity data from familial tumors suggest that BRCA1, a gene that confers susceptibility to ovarian and early-onset breast cancer, encodes a tumor suppressor. The …
sciencemag.org
harvard.edu
osti.gov参考文章(19)
Hans Albertsen, Seppo Pyrhönen, Ulf-Håkan Stenman, Paul Salmikangas, Heli A. Nevanlinna, Craig S. Cropp, Ray White, Robert Callahan, Evidence for involvement of BRCA1 in sporadic breast carcinomas. Cancer Research. ,vol. 54, pp. 2548- 2551 ,(1994)
Katherine E. McKenzie, Christine A. White, Saraswati Sukumar, Oleg K. Glebov, Frequent p53 Gene Mutations and Novel Alleles in Familial Breast Cancer Cancer Research. ,vol. 54, pp. 3703- 3709 ,(1994)
Fujio Kasumi, Satoru Sagae, Ryuichi Kudo, Johji Inazawa, Sumiko Koi, Kiichiro Noda, Hiroko Saito, Junko Saito, Yusuke Nakamura, Susumu Saito, Detailed Deletion Mapping of Chromosome 17q in Ovarian and Breast Cancers: 2-cM Region on 17q21.3 Often and Commonly Deleted in Tumors Cancer Research. ,vol. 53, pp. 3382- 3385 ,(1993)
Fujio Kasumi, Futoshi Akiyama, Goi Sakamoto, Takaaki Sato, Yusuke Nakamura, Accumulation of Genetic Alterations and Progression of Primary Breast Cancer Cancer Research. ,vol. 51, pp. 5794- 5799 ,(1991)
Ford, D, Easton, DF, Bishop, DT, Narod, SA, Goldgar, DE and the Breast Cancer Linkage Consortium, None, Risks of cancer in BRCA1-mutation carriers The Lancet. ,vol. 343, pp. 692- 695 ,(1994) , 10.1016/S0140-6736(94)91578-4
S.A. Smith, D.F. Easton, D.G.R. Evans, B.A.J. Ponder, Allele losses in the region 17q12-21 in familial breast and ovarian cancer involve the wild-type chromosome Nature Genetics. ,vol. 2, pp. 128- 131 ,(1992) , 10.1038/NG1092-128
Henry T. Lynch, Mary Lee fitzsimmons, Theresa A. Conway, Chhanda Bewtra, Jane Lynch, Hereditary carcinoma of the ovary and associated cancers: a study of two families. Gynecologic Oncology. ,vol. 36, pp. 48- 55 ,(1990) , 10.1016/0090-8258(90)90107-V
David P. Keisell, Donald M. Black, D. Timothy Bishop, Nigel K. Spurr, Genetic analysis of the BRCA1 region in a large breast/ovarian family: refinement of the minimal region containing BRCA1 Human Molecular Genetics. ,vol. 2, pp. 1823- 1828 ,(1993) , 10.1093/HMG/2.11.1823
J. Hall, M. Lee, B Newman, J. Morrow, L. Anderson, B Huey, M. King, Linkage of early-onset familial breast cancer to chromosome 17q21 Science. ,vol. 250, pp. 1684- 1689 ,(1990) , 10.1126/SCIENCE.2270482
J. R. Marks, R. W. Wiseman, C. Cochran, P. A. Futreal, P. Söderkvist, P. Söderkvist, P. Söderkvist, J. D. Iglehart, J. C. Barrett, Detection of Frequent Allelic Loss on Proximal Chromosome 17q in Sporadic Breast Carcinoma Using Microsatellite Length Polymorphisms Cancer Research. ,vol. 52, pp. 2624- 2627 ,(1992)