Mouse immune interferon (IFN-γ) gene is on chromosome 10
作者： S. L. Naylor , P. W. Gray , P. A. Lalley
DOI: 10.1007/BF01534857
关键词:
摘要: A cDNA clone for mouse immune interferon has been used to map the γ gene (Ifg)to a specific chromosome. This clone, which contains 638-bp insert, detects an 18-kb HindIII fragment of DNA. The presence Ifgtgene in cell hybrids and its chromosomal location were determined by assaying hybrid DNA Southern filter hybridization. Under hybridization conditions used, Chinese hamster did not hybridize probe. segregation chromosomes indicated that Ifgis located on chromosome 10. Previously, we have mapped p12.05 → qter region 12 humans (1). also genes peptidase B citrate synthase. homologous are 10, suggesting these comprise conserved linkage group.
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