Methods and kits for the diagnosis of prostate cancer

作者: Juan Morote Robles , Jaume Reventós Puigjaner , Andreas Doll , Marina Rigau Resina , Miguel Abal Posada

DOI:

关键词:

摘要: The invention relates to methods and kits for the diagnosis of prostate cancer (PCa) in a subject, assessing or monitoring response therapy subject having PCa progression based on detection alteration expression levels at least one gene selected from group PC A3, PSMA PSGR. as well whether has be subjected biopsy, said serum PSA range within 4-10 ng/mL.

参考文章(36)
Jonathan L. Wright, Paul H. Lange, Newer potential biomarkers in prostate cancer. Reviews in urology. ,vol. 9, pp. 207- ,(2007)
Ellen M. Beasley, Richard M. Myers, David R. Cox, Laura C. Lazzeroni, Statistical refinement of primer design parameters PCR Applications#R##N#Protocols for Functional Genomics. pp. 55- 71 ,(1999) , 10.1016/B978-012372185-3/50006-7
Michael A. Innis, David H. Gelfand, John J. Sninsky, PCR Applications: Protocols for Functional Genomics ,(1999)
David G Bostwick, Leonard S Marks, Prostate Cancer Specificity of PCA3 Gene Testing: Examples from Clinical Practice. Reviews in urology. ,vol. 10, pp. 175- 181 ,(2008)
Gyorgy Petrovics, Chen Sun, Taduru Sreenath, Albert L. Dobi, Shiv K. Srivastava, Prostate cancer-specific alterations in erg gene expression and detection and treatment methods based on those alterations ,(2007)
William Brewster Isaacs, Marion J. G. Bussemakers, Pca3, pca3 genes, and methods of use ,(1998)
Camille Chypre, Genevieve Garon, Yves Fradet, Lyson Piche, Method to detect prostate cancer in a sample ,(2004)
Shubhangi Kamatkar, Manjula Gannavarapu, Karen Glatt, Sebastian Hoersch, Bella Gorbatcheva, Xumei Zhao, Dustin Anderson, Angela Quinn, Robert Schlegel, Wilson Endege, John Monahan, Novel genes, compositions, kit, and methods for identification, assessment, prevention and therapy of prostate cancer ,(2002)
Chunzhi Xia, Wenbin Ma, Fen Wang, Shao-bing Hua, Mingyao Liu, Identification of a prostate-specific G-protein coupled receptor in prostate cancer. Oncogene. ,vol. 20, pp. 5903- 5907 ,(2001) , 10.1038/SJ.ONC.1204803
Outi R. Saramäki, Anna E. Harjula, Paula M. Martikainen, Robert L. Vessella, Teuvo L.J. Tammela, Tapio Visakorpi, TMPRSS2:ERG Fusion Identifies a Subgroup of Prostate Cancers with a Favorable Prognosis Clinical Cancer Research. ,vol. 14, pp. 3395- 3400 ,(2008) , 10.1158/1078-0432.CCR-07-2051