Astrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signaling

作者: S-G Lee , Z-Z Su , L Emdad , D Sarkar , T F Franke

DOI: 10.1038/SJ.ONC.1210713

关键词:

摘要: … -ras as well as functioning as a downstream target gene of Ha… pathways may be one mechanism by which AEG-1 exerts its … PI3K-Akt signaling pathways and downstream signaling …

参考文章(43)
Binhua P. Zhou, Yong Liao, Weiya Xia, Yiyu Zou, Bill Spohn, Mien-Chie Hung, HER-2 / neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation Nature Cell Biology. ,vol. 3, pp. 973- 982 ,(2001) , 10.1038/NCB1101-973
Weiya Xia, Bill Spohn, Mong-Hong Lee, Mien-Chie Hung, Binhua P. Zhou, Yong Liao, Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nature Cell Biology. ,vol. 3, pp. 245- 252 ,(2001) , 10.1038/35060032
Gerard I. Evan, Karen H. Vousden, Proliferation, cell cycle and apoptosis in cancer Nature. ,vol. 411, pp. 342- 348 ,(2001) , 10.1038/35077213
Roger E. McLendon, Christopher M. Counter, Darell D. Bigner, Jeremy N. Rich, Chuanhai Guo, Xiao-Fan Wang, A genetically tractable model of human glioma formation. Cancer Research. ,vol. 61, pp. 3556- 3560 ,(2001)
Osman Nidai Ozes, Lindsey D Mayo, Jason A Gustin, Susan R Pfeffer, Lawrence M Pfeffer, David B Donner, None, NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase Nature. ,vol. 401, pp. 82- 85 ,(1999) , 10.1038/43466
Thomas F. Franke, Lewis C. Cantley, Apoptosis. A Bad kinase makes good. Nature. ,vol. 390, pp. 116- 117 ,(1997) , 10.1038/36442
Deborah A Altomare, Joseph R Testa, Perturbations of the AKT signaling pathway in human cancer Oncogene. ,vol. 24, pp. 7455- 7464 ,(2005) , 10.1038/SJ.ONC.1209085
Dong-chul Kang, Zao-zhong Su, Devanand Sarkar, Luni Emdad, David J. Volsky, Paul B. Fisher, Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1 Gene. ,vol. 353, pp. 8- 15 ,(2005) , 10.1016/J.GENE.2005.04.006
Jill A. White, Stephen G. Carter, Harvey L. Ozer, Ann L. Boyd, Cooperativity of SV40 T antigen and ras in progressive stages of transformation of human fibroblasts. Experimental Cell Research. ,vol. 203, pp. 157- 163 ,(1992) , 10.1016/0014-4827(92)90051-9