Long-term continuous exposure to sulfur dioxide and fly ash mixtures in cynomolgus monkeys and guinea pigs.

作者: Yves Alarie , Robert J. Kantz , Charles E. Ulrich , Alexis A. Krumm , William M. Busey

DOI: 10.1080/00039896.1973.10666363

关键词: Sulfur dioxidePulmonary function testingToxicologyFly ashContinuous exposureExposure periodChemistryAnimal science

摘要: Three groups of cynomolgus monkeys and three guinea pigs were exposed to mixtures sulfur dioxide (SO2) fly ash while one group each species was used as a control group. The exposure concentrations for SO2 0.1, 1.0, 5 ppm, 0.5 mg/cu m combined with the concentrations. duration 52 weeks in 78 monkeys. Pulmonary function tests serum biochemical hematological analyses conducted prior during period. At termination exposure, microscopic examination lung performed. Analysis data revealed that no adverse effects or could he attributed ash.

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