Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
作者： Shiqing Li , Karl R. Schmitz , Philip D. Jeffrey , Jed J.W. Wiltzius , Paul Kussie
DOI: 10.1016/J.CCR.2005.03.003
关键词: Cell biology 、 Antibody 、 Cetuximab 、 Receptor 、 Matuzumab 、 Inhibitory postsynaptic potential 、 Extracellular 、 Immunology 、 Immune system 、 Epidermal growth factor receptor 、 Chemistry
摘要: … Further, since cetuximab is an inhibitor of EGFR, this also strengthens our conclusion that the tethered form represents an inactive state of the EGFR extracellular region. Minor …
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