Carcinoembryonic antigen, a human tumor marker, functions as an intercellular adhesion molecule.

作者: Sarita Benchimol , Abraham Fuks , Serge Jothy , Nicole Beauchemin , Kinji Shirota

DOI: 10.1016/0092-8674(89)90970-7

关键词: Carcinoembryonic antigenBiologyImmunologyIntercellular adhesion moleculeIntestinal epitheliumTransfectionEpitheliumAdenocarcinomaCell adhesion moleculeCancer researchMalignant transformation

摘要: … The function of this widely used tumor marker and its … We also show that, whereas CEA is localized mainly to epithelial … LR-73 transfectant clones bearing the marker were selected; only …

参考文章(40)
Minnie Mathan, Pamela C. Moxey, Jerry S. Trier, Morphogenesis of fetal rat duodenal villi American Journal of Anatomy. ,vol. 146, pp. 73- 92 ,(1976) , 10.1002/AJA.1001460104
R. J. Paxton, G. Mooser, H. Pande, T. D. Lee, J. E. Shively, Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene family. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 920- 924 ,(1987) , 10.1073/PNAS.84.4.920
Akinao Nose, Akira Nagafuchi, Masatoshi Takeichi, Expressed recombinant cadherins mediate cell sorting in model systems Cell. ,vol. 54, pp. 993- 1001 ,(1988) , 10.1016/0092-8674(88)90114-6
Timothy V. Updyke, Garth L. Nicolson, Malignant melanoma cell lines selected in vitro for increased homotypic adhesion properties have increased experimental metastatic potential Clinical & Experimental Metastasis. ,vol. 4, pp. 273- 284 ,(1986) , 10.1007/BF00133592
Hideko Urushihara, Hiroki S. Ozaki, Masatoshi Takeichi, Immunological detection of cell surface components related with aggregation of Chinese hamster and chick embryonic cells. Developmental Biology. ,vol. 70, pp. 206- 216 ,(1979) , 10.1016/0012-1606(79)90017-4
W. Zimmermann, B. Ortlieb, R. Friedrich, S. von Kleist, Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure Proceedings of the National Academy of Sciences of the United States of America. ,vol. 84, pp. 2960- 2964 ,(1987) , 10.1073/PNAS.84.9.2960