Successful pregnancy with nocturnal hemodialysis.

摘要: A 31-year-old woman with end-stage renal disease was referred to the Toronto General Hospital (Ontario, Canada) for conversion from conventional hemodialysis (CHD; 4 h/session, 3 sessions/wk) nocturnal (NHD; 7 5 6 treatments/wk) because of refractory hypertension. As expected, blood pressure control superior NHD therapy, and her requirement vasoactive medications also decreased. To our surprise, 8 months after she regained normal menstrual cycles. Two years therapy initiation, patient became pregnant, at which time dialysis prescription changed 7.5 nights/wk. During pregnancy, well controlled, biochemical, hematologic, metabolic parameters were targeted physiological levels. The had an uncomplicated vaginal delivery a healthy 3,025-g infant 38 weeks' gestation. This case shows that on able resume ovulation have pregnancy. We speculate augmentation uremic clearance by means pivotal in maintaining nonproblematic Future studies are required further understand impact intensive reproductive endocrine functions determine best management such patients during