Structural Changes of Collagen Components and Diminution of Nerves in Congenital Ureteropelvic Junction Obstruction

作者: Masashi Murakumo , Katsuya Nonomura , Tetsufumi Yamashita , Tatsuo Ushiki , Kazuhiro Abe

DOI: 10.1016/S0022-5347(01)64910-3

关键词: PathologyIntrinsic obstructionBasement membraneDiminutionCongenital Ureteropelvic Junction ObstructionImmunohistochemistryMedicineHistologyAnatomyStructural componentMyocyte

摘要: AbstractPurpose: Three-dimensional arrangements of smooth muscle cells, collagenous component and peripheral nerves congenital ureteropelvic junction (UPJ) obstruction were studied in order to clarify the pathogenetic mechanism interaction among these neuro-myo-stromal components.Materials Methods: The UPJ upper ureters obtained from 14 patients with hydronephrosis (7 intrinsic 4 extrinsic obstruction) 7 normal controls. arrangement each structural was observed by scanning electron microscopy, nerve distribution analyzed immunohistochemistry for protein gene product 9.5.Results: had features as follows. Muscle fascicles sparse thin. Each cell thin diameter. Intercellular spaces six seven times wider than Collagen fibrillar sheaths cells (pericellular collagen fibrils attached basement membrane) interwoven ...

参考文章(20)
Moneer K. Hanna, Robert D. Jeffs, Jennifer M. Sturgess, Martin Barkin, Ureteral Structure and Ultrastructure. Part II. Congenital Ureteropelvic Junction Obstruction and Primary Obstructive Megaureter The Journal of Urology. ,vol. 116, pp. 725- 730 ,(1976) , 10.1016/S0022-5347(17)58987-9
Masashi Murakumo, Tatsuo Ushiki, Kazuhiro Abe, Kinya Matsumura, Yuichiro Shinno, Tomohiko Koyanagi, Three-Dimensional Arrangement of Collagen and Elastin Fibers in the Human Urinary Bladder: A Scanning Electron Microscopic Study * The Journal of Urology. ,vol. 154, pp. 251- 256 ,(1995) , 10.1016/S0022-5347(01)67289-6
Masashi MURAKUMO, Tatsuo USHIKI, Tomohiko KOYANAGI, Kazuhiro ABE, Scanning Electron Microscopic Studies of Smooth Muscle Cells and Their Collagen Fibrillar Sheaths in Empty, Distended and Contracted Urinary Bladders of the Guinea Pig. Archives of Histology and Cytology. ,vol. 56, pp. 441- 449 ,(1993) , 10.1679/AOHC.56.441
Katherine A. Edyvane, Dianne C. Trussell, Jamila Jonavicius, Anthony Henwood, Villis R. Marshall, Presence and regional variation in peptide-containing nerves in the human ureter. Journal of The Autonomic Nervous System. ,vol. 39, pp. 127- 137 ,(1992) , 10.1016/0165-1838(92)90053-J
Richard G. Notley, ELECTRON MICROSCOPY OF THE UPPER URETER AND THE PELVI-URETERIC JUNCTION British Journal of Urology. ,vol. 40, pp. 37- 52 ,(2008) , 10.1111/J.1464-410X.1968.TB11811.X
R.J. Thompson, J.F. Doran, P. Jackson, A.P. Dhillon, J. Rode, PGP 9.5—a new marker for vertebrate neurons and neuroendocrine cells Brain Research. ,vol. 278, pp. 224- 228 ,(1983) , 10.1016/0006-8993(83)90241-X
Tatsuo USHIKI, Masashi MURAKUMO, Scanning Electron Microscopic Studies of Tissue Elastin Components Exposed by a KOH-Collagenase or Simple KOH Digestion Method. Archives of Histology and Cytology. ,vol. 54, pp. 427- 436 ,(1991) , 10.1679/AOHC.54.427