Combined inhibition of VEGF and PDGF signaling enforces tumor vessel regression by interfering with pericyte-mediated endothelial cell survival mechanisms

作者: Ralf Erber , Andreas Thurnher , Alice D. Katsen , Gesine Groth , Heinz Kerger

DOI: 10.1096/FJ.03-0271FJE

关键词:

摘要: … or by taking advantage of negative regulators of angiogenesis. Vascular endothelial growth factor (VEGF) has been shown to be the central positive regulator of tumor angiogenesis and…

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