WT1, MSH6 , GATA5 and PAX5 as epigenetic oral squamous cell carcinoma biomarkers - a short report

作者: Ilda Patrícia Ribeiro , Francisco Caramelo , Francisco Marques , Ana Domingues , Margarida Mesquita

DOI: 10.1007/S13402-016-0293-5

关键词:

摘要: Purpose Oral squamous cell carcinoma (OSCC) is a frequently occurring aggressive malignancy with heterogeneous clinical behavior. Based on the paucity of specific early diagnostic and prognostic biomarkers, which hampers appropriate treatment and, ultimately development novel targeted therapies, we aimed at identifying such biomarkers through genetic epigenetic analysis these tumors.

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